"#Table S24. Gene identity, abundance, annotation and expression profile of proteins isolated from shells of C. gigas." Gene_ID Secreted protein* No. of unique peptide No. of unique spectrum pI IPR annotation Nr annotation Mantle (Man) Female gonad (Fgo) Adductor muscle (Amu) Hemolymph (Hem) Digest gland (Dgl) Gill (Gil) Labial palp (Lpa) Male gonad (Mgo) CGI_10023898 No 1 1 4.21 IPR002048; Calcium-binding EF-hand IPR018248; EF-hand IPR018249; EF-HAND 2 hypothetical protein BRAFLDRAFT_124868 [Branchiostoma floridae] gb|EEN49263.1| hypothetical protein BRAFLDRAFT_124868 [Branchiostoma floridae] 9.7 12.1 2.2 0.3 16.4 70.6 93.8 35.6 CGI_10020039 No 1 1 4.26 " IPR000233; Cadherin, cytoplasmic domain IPR000742; Epidermal growth factor-like, type 3 IPR002126; Cadherin IPR006210; Epidermal growth factor-like IPR015919; Cadherin-like " GF15089 [Drosophila ananassae] gb|EDV30907.1| GF15089 [Drosophila ananassae] 0.3 33.6 0.1 0.3 40.2 0.4 0.4 20.2 CGI_10006505 Yes 3 11 4.30 60.6 2.2 1.7 1.1 5.8 1.5 1.8 0.4 CGI_10016585 No 3 16 4.30 IPR002048; Calcium-binding EF-hand IPR018248; EF-hand IPR018249; EF-HAND 2 PREDICTED: similar to calmodulin [Acyrthosiphon pisum] 4.6 0.1 0.0 0.1 0.3 0.4 0.0 0.3 CGI_10007530 Yes 1 1 4.34 dopamine beta hydroxylase-like protein [Pomatoceros lamarckii] 70.7 0.0 1.0 0.2 3.6 0.8 0.0 0.4 CGI_10007556 Yes 1 1 4.39 large adhesin [Haemophilus somnus 129PT] gb|ABI25900.1| conserved hypothetical protein [Haemophilus somnus 129PT] 585.2 0.5 5.6 0.0 30.9 0.3 0.0 0.9 CGI_10005015 No 1 3 4.45 IPR002110; Ankyrin repeat IPR020683; Ankyrin repeat-containing domain ankyrin repeat domain protein [Wolbachia endosymbiont of Culex quinquefasciatus Pel] ref|ZP_03335037.1| ankyrin repeat domain protein [Wolbachia endosymbiont of Culex quinquefasciatus JHB] emb|CAQ55486.1| ankyrin repeat domain protein [Wolbachia endosymbiont of Culex quinquefasciatus Pel] gb|EEB55980.1| ankyrin repeat domain protein [Wolbachia endosymbiont of Culex quinquefasciatus JHB] 0.0 0.2 0.3 0.0 0.0 9.9 0.0 0.1 CGI_10019835 No 1 1 4.48 " IPR000217; Tubulin IPR002453; Beta tubulin IPR003008; Tubulin/FtsZ, GTPase domain IPR008280; Tubulin/FtsZ, C-terminal IPR018316; Tubulin/FtsZ, 2-layer sandwich domain " beta-tubulin [Crassostrea gigas] 59.1 1053.5 78.4 13.9 608.2 2728.2 149.5 717.3 CGI_10012144 No 1 1 4.49 " IPR000306; Zinc finger, FYVE-type IPR011011; Zinc finger, FYVE/PHD-type IPR017455; Zinc finger, FYVE-related " "zinc finger protein FYVE domain containing protein, putative [Pediculus humanus corporis] gb|EEB16814.1| zinc finger protein FYVE domain containing protein, putative [Pediculus humanus corporis]" 16.8 15.3 22.5 18.7 14.3 15.6 16.2 11.2 CGI_10010359 No 5 9 4.51 IPR008985; Concanavalin A-like lectin/glucanase RecName: Full=Shell matrix protein 359.7 1.2 4.2 0.6 25.1 10.6 3.5 28.5 CGI_10022252 No 1 3 4.54 IPR000436; Sushi/SCR/CCP IPR016060; Complement control module hypothetical protein BRAFLDRAFT_68380 [Branchiostoma floridae] gb|EEN69394.1| hypothetical protein BRAFLDRAFT_68380 [Branchiostoma floridae] 0.6 0.4 0.8 0.2 0.5 0.6 1.6 0.3 CGI_10012352 No 3 10 4.59 IPR002557; Chitin binding domain IPR003598; Immunoglobulin subtype 2 IPR003599; Immunoglobulin subtype IPR007110; Immunoglobulin-like IPR008985; Concanavalin A-like lectin/glucanase IPR013098; Immunoglobulin I-set RecName: Full=PIF; Contains: RecName: Full=Pif97; Contains: RecName: Full=Pif80; AltName: Full=Aragonite-binding protein; Flags: Precursor dbj|BAH97338.1| Pif177 [Pinctada fucata] 214.1 1.8 2.0 0.0 11.1 6.8 0.0 8.9 CGI_10012353 No 2 5 4.60 IPR002557; Chitin binding domain 232.5 0.4 2.1 0.1 11.7 6.1 0.0 5.7 CGI_10021657 No 1 2 4.61 " IPR002223; Proteinase inhibitor I2, Kunitz metazoa " hypothetical protein BRAFLDRAFT_199584 [Branchiostoma floridae] gb|EEN49737.1| hypothetical protein BRAFLDRAFT_199584 [Branchiostoma floridae] 19.4 5.1 0.3 1.4 49.9 1.1 2.2 2.0 CGI_10018678 No 1 1 4.64 hypothetical protein BRAFLDRAFT_81769 [Branchiostoma floridae] gb|EEN55115.1| hypothetical protein BRAFLDRAFT_81769 [Branchiostoma floridae] 6.2 5.9 3.0 6.5 6.4 6.5 7.1 7.3 CGI_10013347 No 2 7 4.67 " IPR000194; ATPase, alpha/beta subunit, nucleotide-binding domain IPR000793; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal IPR003593; ATPase, AAA+ type, core " ATP synthase beta subunit [Pinctada fucata] 327.0 470.8 421.1 268.9 247.3 301.8 234.6 391.3 CGI_10004620 No 2 4 4.69 " IPR011105; Cell wall hydrolase, SleB " spore cortex-lytic enzyme prepeptide [Heliobacterium modesticaldum Ice1] gb|ABZ85060.1| spore cortex-lytic enzyme prepeptide [Heliobacterium modesticaldum Ice1] 2.6 0.0 0.2 0.2 0.1 0.0 0.0 4.8 CGI_10012276 No 1 2 4.70 " IPR000601; PKD domain IPR002859; PKD/REJ-like protein IPR003915; Polycystic kidney disease type 2 protein IPR013122; Polycystin cation channel, PKD1/PKD2 " PREDICTED: receptor for egg jelly 6-like [Saccoglossus kowalevskii] 6.7 1.5 1.1 2.0 0.8 4.0 7.1 4.0 CGI_10012163 No 1 1 4.72 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 CGI_10009101 No 1 2 4.74 hypothetical protein BRAFLDRAFT_63397 [Branchiostoma floridae] gb|EEN44459.1| hypothetical protein BRAFLDRAFT_63397 [Branchiostoma floridae] 127.7 50.2 57.6 452.0 40.7 54.3 40.4 43.1 CGI_10021965 No 1 2 4.74 1.1 0.5 0.8 0.0 0.4 15.8 0.1 0.4 CGI_10003000 Yes 5 20 4.77 IPR001073; Complement C1q protein IPR008983; Tumour necrosis factor-like putative C1q domain containing protein MgC1q25 [Mytilus galloprovincialis] 37.1 0.1 0.3 0.0 1.9 0.8 0.1 1.6 CGI_10028542 No 1 1 4.78 " IPR001623; Heat shock protein DnaJ, N-terminal IPR002939; Chaperone DnaJ, C-terminal IPR003095; Heat shock protein DnaJ IPR008160; Collagen triple helix repeat IPR008971; HSP40/DnaJ peptide-binding IPR008985; Concanavalin A-like lectin/glucanase IPR010515; Collagenase NC10/endostatin IPR016187; C-type lectin fold " hypothetical protein BRAFLDRAFT_79829 [Branchiostoma floridae] gb|EEN53941.1| hypothetical protein BRAFLDRAFT_79829 [Branchiostoma floridae] 219.3 121.0 57.0 35.7 98.1 136.6 170.4 107.0 CGI_10028014 Yes 2 3 4.79 " IPR002035; von Willebrand factor, type A IPR002557; Chitin binding domain " RecName: Full=PIF; Contains: RecName: Full=Pif97; Contains: RecName: Full=Pif80; AltName: Full=Aragonite-binding protein; Flags: Precursor dbj|BAH97338.1| Pif177 [Pinctada fucata] 197.9 0.4 1.9 0.0 12.8 5.9 0.1 24.5 CGI_10022748 No 1 1 4.87 " IPR001005; SANT domain, DNA binding IPR009057; Homeodomain-like " PREDICTED: similar to transcription factor-like nuclear regulator [Gallus gallus] 6.8 25.3 7.0 14.4 10.6 10.1 9.4 14.6 CGI_10017544 Yes 7 37 4.88 " IPR000742; Epidermal growth factor-like, type 3 IPR001507; Endoglin/CD105 antigen IPR006210; Epidermal growth factor-like " RecName: Full=Gigasin-2; Flags: Precursor 100.7 0.0 1.3 0.1 5.6 2.9 0.0 9.6 CGI_10016016 No 1 1 4.88 " IPR000436; Sushi/SCR/CCP IPR002035; von Willebrand factor, type A IPR002557; Chitin binding domain IPR008985; Concanavalin A-like lectin/glucanase IPR016060; Complement control module " hypothetical protein BRAFLDRAFT_103544 [Branchiostoma floridae] gb|EEN62858.1| hypothetical protein BRAFLDRAFT_103544 [Branchiostoma floridae] 35.1 0.4 0.2 0.1 1.7 1.0 0.0 1.6 CGI_10010935 No 1 2 4.88 " IPR003598; Immunoglobulin subtype 2 IPR003599; Immunoglobulin subtype IPR007110; Immunoglobulin-like IPR009134; Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal IPR013098; Immunoglobulin I-set IPR013106; Immunoglobulin V-set " AGAP004108-PA [Anopheles gambiae str. PEST] gb|EAA08671.4| AGAP004108-PA [Anopheles gambiae str. PEST] 0.4 0.2 0.4 0.0 0.2 0.2 0.1 19.5 CGI_10022466 No 1 1 4.88 " IPR000436; Sushi/SCR/CCP IPR001846; von Willebrand factor, type D domain IPR003886; Nidogen, extracellular domain IPR005533; AMOP IPR016060; Complement control module " PREDICTED: predicted protein-like [Saccoglossus kowalevskii] 18.5 6.5 29.2 1.9 12.9 17.3 40.0 8.0 CGI_10018952 No 1 4 4.91 199.4 5.8 1.8 29.8 15.3 12.9 3.5 8.2 CGI_10024145 No 1 1 4.92 IPR000210; BTB/POZ-like IPR006652; Kelch repeat type 1 IPR011333; BTB/POZ fold IPR011705; BTB/Kelch-associated IPR013069; BTB/POZ PREDICTED: kelch-like 24 (Drosophila) [Taeniopygia guttata] 0.2 0.5 1.7 0.8 0.5 0.1 0.1 0.1 CGI_10025876 No 1 2 4.93 " IPR000742; Epidermal growth factor-like, type 3 IPR000859; CUB IPR000998; MAM domain IPR001506; Peptidase M12A, astacin IPR001881; EGF-like calcium-binding IPR006026; Peptidase, metallopeptidase IPR006210; Epidermal growth factor-like IPR008985; Concanavalin A-like lectin/glucanase " PREDICTED: similar to apical endosomal glycoprotein [Strongylocentrotus purpuratus] ref|XP_001194828.1| PREDICTED: similar to apical endosomal glycoprotein [Strongylocentrotus purpuratus] 0.3 7.3 0.4 2.1 2.1 21.1 7.8 3.5 CGI_10014850 No 1 1 4.94 " IPR001791; Laminin G domain IPR002049; EGF-like, laminin IPR003961; Fibronectin, type III IPR006558; LamG-like jellyroll fold IPR008211; Laminin, N-terminal IPR008957; Fibronectin type III domain IPR008979; Galactose-binding domain-like IPR008985; Concanavalin A-like lectin/glucanase IPR012680; Laminin G, subdomain 2 " PREDICTED: similar to Usher syndrome 2A [Strongylocentrotus purpuratus] ref|XP_001179293.1| PREDICTED: similar to Usher syndrome 2A [Strongylocentrotus purpuratus] 2.2 5.1 1.5 1.6 2.0 1.5 1.0 1.0 CGI_10009758 No 1 2 4.96 " IPR000315; Zinc finger, B-box IPR001841; Zinc finger, RING-type IPR002999; Tudor domain IPR008191; Maternal tudor protein IPR018351; Tudor subgroup " PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] ref|XP_001191141.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] 4.7 9.5 5.8 5.5 6.5 4.9 6.2 9.6 CGI_10019135 No 1 6 4.96 IPR002937; Amine oxidase spermine oxidase [Xenopus (Silurana) tropicalis] emb|CAJ81958.1| spermine oxidase [Xenopus (Silurana) tropicalis] 41.8 45.4 31.2 62.4 39.9 36.5 37.2 48.6 CGI_10016467 No 1 1 4.97 IPR001190; Speract/scavenger receptor IPR017448; Speract/scavenger receptor-related "PREDICTED: similar to scavenger receptor cysteine-rich protein type 12 precursor, partial [Strongylocentrotus purpuratus] ref|XP_001180320.1| PREDICTED: similar to scavenger receptor cysteine-rich protein type 12 precursor, partial [Strongylocentrotus purpuratus]" 0.1 0.1 0.0 0.4 0.0 0.2 0.1 1.4 CGI_10023765 No 3 23 5.01 " IPR001599; Alpha-2-macroglobulin IPR008930; Terpenoid cylases/protein prenyltransferase alpha-alpha toroid IPR009048; Alpha-macroglobulin, receptor-binding IPR011626; A-macroglobulin complement component IPR019565; Alpha-2-macroglobulin, thiol-ester bond-forming " thioester-containing protein [Chlamys farreri] 75.2 29.1 48.9 2.6 22.9 8.3 17.6 23.1 CGI_10012348 No 20 84 5.01 IPR002557; Chitin binding domain IPR003598; Immunoglobulin subtype 2 IPR003599; Immunoglobulin subtype IPR007110; Immunoglobulin-like IPR008985; Concanavalin A-like lectin/glucanase IPR013098; Immunoglobulin I-set IPR013151; Immunoglobulin "PREDICTED: hemicentin 1, partial [Oryctolagus cuniculus]" 83.4 0.4 1.5 0.0 3.8 1.3 0.1 1.9 CGI_10023506 No 1 2 5.02 " IPR005084; Carbohydrate binding domain, family 6 " 62.1 0.4 0.1 0.0 3.8 4.4 0.1 3.3 CGI_10020694 No 1 1 5.03 IPR001304; C-type lectin IPR016187; C-type lectin fold C-type lectin C [Chlamys farreri] 182.0 1.4 2.1 1.0 90.6 2.7 0.0 14.7 CGI_10022683 Yes 1 1 5.05 0.1 1.8 0.0 0.0 0.5 0.0 0.1 0.2 CGI_10026148 Yes 1 3 5.07 " IPR001424; Superoxide dismutase, copper/zinc binding " dominin precursor [Crassostrea virginica] 3396.9 1686.4 994.3 164.4 2278.4 1737.4 2666.6 1938.6 CGI_10026432 Yes 1 1 5.08 expressed hypothetical protein [Trichoplax adhaerens] gb|EDV27620.1| expressed hypothetical protein [Trichoplax adhaerens] 25.9 1.2 0.0 0.1 2.2 0.8 1.3 0.2 CGI_10028056 No 1 1 5.15 IPR000569; HECT unnamed protein product [Tetraodon nigroviridis] 20.4 26.2 51.0 61.5 23.2 22.7 23.1 26.9 CGI_10002951 No 1 9 5.17 9.6 10.0 2.7 148.5 6.3 15.0 7.0 5.1 CGI_10006331 No 1 3 5.19 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 CGI_10005985 No 1 1 5.21 IPR006575; RWD domain IPR010541; Domain of unknown function DUF1115 IPR016135; Ubiquitin-conjugating enzyme/RWD-like PREDICTED: RWD domain containing 2B-like [Saccoglossus kowalevskii] 12.2 15.5 11.8 22.5 11.4 9.4 12.6 6.7 CGI_10019671 No 1 17 5.21 hypothetical protein BRAFLDRAFT_118709 [Branchiostoma floridae] gb|EEN69302.1| hypothetical protein BRAFLDRAFT_118709 [Branchiostoma floridae] 20.6 12.4 6.5 9.4 27.7 23.1 35.9 15.4 CGI_10022093 No 1 1 5.22 " IPR000048; IQ motif, EF-hand binding site IPR001609; Myosin head, motor domain IPR002928; Myosin tail IPR004009; Myosin, N-terminal, SH3-like IPR008989; Myosin S1 fragment, N-terminal IPR009053; Prefoldin IPR010978; tRNA-binding arm " pedal retractor muscle myosin heavy chain [Mytilus galloprovincialis] 364.1 1.7 4965.8 41.5 4.2 8.5 5.1 5.0 CGI_10018174 No 1 3 5.22 11.4 0.0 0.2 0.0 0.7 0.2 0.0 0.8 CGI_10003410 No 1 1 5.26 IPR009053; Prefoldin PREDICTED: centrosomal protein 290kDa-like [Saccoglossus kowalevskii] 3.8 8.0 2.1 4.5 4.8 10.4 11.2 14.5 CGI_10016969 No 1 2 5.26 0.4 0.0 0.0 0.0 0.1 0.0 0.5 0.3 CGI_10024210 No 1 1 5.29 " IPR007087; Zinc finger, C2H2-type IPR015880; Zinc finger, C2H2-like IPR017956; AT hook, DNA-binding motif IPR020478; AT hook-like " PREDICTED: similar to Zinc finger protein 57 (Zinc finger protein 424) [Equus caballus] 9.7 23.3 14.1 19.4 11.1 9.9 9.9 14.6 CGI_10005782 No 1 1 5.29 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CGI_10001975 Yes 1 2 5.31 " IPR002502; N-acetylmuramoyl-L-alanine amidase, family 2 IPR006619; Peptidoglycan recognition protein, metazoa/bacteria " peptidoglycan recognition protein S1L [Crassostrea gigas] 66.0 9.5 27.4 11.6 14.2 87.4 21.8 5.0 CGI_10017629 No 1 1 5.31 " IPR008967; p53-like transcription factor, DNA-binding IPR013801; STAT transcription factor, DNA-binding " PREDICTED: signal transducer and activator of transcription 5B-like isoform 4 [Macaca mulatta] 22.0 9.9 17.6 19.5 9.8 9.8 12.8 21.0 CGI_10018997 No 1 1 5.35 IPR000033; LDLR class B repeat IPR006210; Epidermal growth factor-like PREDICTED: similar to Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7) [Strongylocentrotus purpuratus] ref|XP_001193075.1| PREDICTED: similar to Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7) [Strongylocentrotus purpuratus] 48.5 25.4 21.9 10.8 34.4 21.3 27.8 35.8 CGI_10023767 No 13 58 5.36 " IPR002890; Alpha-2-macroglobulin, N-terminal IPR011625; Alpha-2-macroglobulin, N-terminal 2 " thioester-containing protein [Euphaedusa tau] 76.0 24.5 31.5 2.7 20.3 9.3 18.2 33.4 CGI_10001712 No 1 1 5.38 IPR000488; Death IPR011029; DEATH-like 24.1 26.7 15.2 50.4 22.8 46.8 29.0 13.1 CGI_10010994 No 1 1 5.40 " IPR003593; ATPase, AAA+ type, core IPR004273; Dynein heavy chain IPR011704; ATPase, AAA-5 IPR013594; Dynein heavy chain, N-terminal domain-1 IPR013602; Dynein heavy chain, N-terminal domain-2 " "PREDICTED: dynein, axonemal, heavy chain 5-like [Saccoglossus kowalevskii]" 11.8 30.0 3.0 5.3 21.1 129.6 55.9 37.2 CGI_10004086 No 2 6 5.40 " IPR002035; von Willebrand factor, type A IPR002557; Chitin binding domain " RecName: Full=PIF; Contains: RecName: Full=Pif97; Contains: RecName: Full=Pif80; AltName: Full=Aragonite-binding protein; Flags: Precursor dbj|BAH97338.1| Pif177 [Pinctada fucata] 15.0 0.2 0.2 0.1 1.3 0.5 0.1 4.2 CGI_10017660 No 1 1 5.41 " IPR001752; Kinesin, motor domain " kinesin-like protein KIF15 [Strongylocentrotus purpuratus] sp|Q9GYZ0.1|KIF15_STRPU RecName: Full=Kinesin-like protein KIF15; AltName: Full=Kinesin-related protein KRP180 gb|AAG01844.1|AF284333_1 kinesin-like protein KRP180 [Strongylocentrotus purpuratus] 4.5 30.3 6.1 16.8 9.7 7.2 5.2 5.3 CGI_10005733 No 1 1 5.43 13.6 0.9 0.1 8.2 1.2 0.3 0.3 0.4 CGI_10006476 No 1 1 5.44 PREDICTED: ring finger protein 213 [Bos taurus] 16.1 8.1 25.3 6.5 11.6 8.2 12.1 15.9 CGI_10026671 No 2 7 5.45 " IPR000572; Oxidoreductase, molybdopterin-binding domain IPR001199; Cytochrome b5 IPR002035; von Willebrand factor, type A IPR005066; Moybdenum cofactor oxidoreductase, dimerisation IPR006029; Neurotransmitter-gated ion-channel transmembrane domain IPR006201; Neurotransmitter-gated ion-channel IPR006202; Neurotransmitter-gated ion-channel ligand-binding IPR008335; Eukaryotic molybdopterin oxidoreductase IPR014756; Immunoglobulin E-set " predicted protein [Nematostella vectensis] gb|EDO45092.1| predicted protein [Nematostella vectensis] 278.0 6.9 12.1 4.3 30.7 20.9 8.9 9.3 CGI_10004404 No 1 3 5.47 IPR000033; LDLR class B repeat IPR000436; Sushi/SCR/CCP IPR006210; Epidermal growth factor-like IPR016060; Complement control module PREDICTED: low-density lipoprotein receptor-related protein 4-like [Sus scrofa] 0.3 0.2 0.2 0.1 0.0 0.0 0.2 0.4 CGI_10022800 No 2 4 5.49 hypothetical protein RPC_1864 [Rhodopseudomonas palustris BisB18] gb|ABD87421.1| hypothetical protein RPC_1864 [Rhodopseudomonas palustris BisB18] 2.2 0.0 0.0 0.3 0.4 0.0 0.0 0.3 CGI_10018834 Yes 3 18 5.52 " IPR001424; Superoxide dismutase, copper/zinc binding " dominin precursor [Crassostrea virginica] 561.2 348.6 215.2 30.2 492.4 398.7 482.3 1141.0 CGI_10011920 No 1 2 5.54 IPR001870; B302/SPRY domain IPR008985; Concanavalin A-like lectin/glucanase PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] ref|XP_001192797.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] 2.4 11.0 2.0 8.7 5.8 7.5 4.5 3.0 CGI_10008231 Yes 1 3 5.55 rCG54369 [Rattus norvegicus] 22.7 6.7 1.6 7.1 8.0 4.6 3.9 14.8 CGI_10018353 No 1 1 5.55 " IPR011044; Quinoprotein amine dehydrogenase, beta chain-like IPR011046; WD40 repeat-like-containing domain " hypothetical protein DAPPUDRAFT_202786 [Daphnia pulex] 6.7 8.3 8.1 0.7 10.0 12.0 20.9 37.5 CGI_10003506 No 1 1 5.55 0.1 0.0 0.0 0.0 0.6 0.3 0.0 0.0 CGI_10017099 No 1 1 5.57 IPR008636; HOOK IPR009053; Prefoldin PREDICTED: coiled-coil domain containing 88C [Taeniopygia guttata] 9.2 25.6 3.5 13.3 27.3 34.5 40.2 16.5 CGI_10018456 No 1 1 5.59 unnamed protein product [Tetraodon nigroviridis] 9.0 4.6 64.9 7.3 3.2 2.4 2.5 1.6 CGI_10001554 No 1 2 5.60 " IPR001650; Helicase, C-terminal IPR011545; DNA/RNA helicase, DEAD/DEAH box type, N-terminal IPR014001; DEAD-like helicase, N-terminal IPR014021; Helicase, superfamily 1/2, ATP-binding domain " translation initiation factor eIF4A II [Xenopus laevis] 236.0 438.8 438.1 155.7 204.2 146.0 184.4 387.1 CGI_10017696 No 1 2 5.64 IPR001487; Bromodomain IPR021900; Protein of unknown function DUF3512 PREDICTED: similar to conserved hypothetical protein [Nasonia vitripennis] 11.0 101.7 29.0 60.2 27.5 15.3 10.5 19.3 CGI_10027871 No 1 1 5.64 " IPR001540; Glycoside hydrolase, family 20 IPR008965; Carbohydrate-binding IPR015883; Glycoside hydrolase, family 20, catalytic core IPR017853; Glycoside hydrolase, catalytic core " predicted protein [Nematostella vectensis] gb|EDO42823.1| predicted protein [Nematostella vectensis] 0.0 0.2 0.0 0.0 1.5 0.1 0.0 0.8 CGI_10002311 No 1 1 5.66 IPR001585; Transaldolase RecName: Full=Transaldolase gb|AAI09966.1| TALDO1 protein [Bos taurus] 23.8 25.3 10.5 72.7 13.0 16.1 10.9 26.5 CGI_10017263 No 1 1 5.66 " IPR002423; Chaperonin Cpn60/TCP-1 IPR017998; Chaperone, tailless complex polypeptide 1 " hypothetical protein BRAFLDRAFT_119852 [Branchiostoma floridae] gb|EEN69489.1| hypothetical protein BRAFLDRAFT_119852 [Branchiostoma floridae] 24.1 74.5 44.9 56.3 33.6 34.1 24.3 57.0 CGI_10020738 No 1 1 5.68 IPR000859; CUB hypothetical protein TRIADDRAFT_53561 [Trichoplax adhaerens] gb|EDV28197.1| hypothetical protein TRIADDRAFT_53561 [Trichoplax adhaerens] 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.8 CGI_10014170 Yes 3 17 5.69 " IPR000971; Globin, subset IPR001032; Leghaemoglobin IPR001148; Carbonic anhydrase, alpha-class, catalytic domain IPR009050; Globin-like " RecName: Full=Nacrein-like protein 6.1 2.5 0.1 0.6 2.6 2.7 1.5 0.6 CGI_10006472 No 1 1 5.69 IPR000175; Sodium:neurotransmitter symporter IPR002925; Dienelactone hydrolase "sodium-dependent neurotransmitter transporter [Schistosoma mansoni] emb|CAZ29137.1| sodium-dependent neurotransmitter transporter, putative [Schistosoma mansoni]" 41.7 6.9 5.3 12.2 33.3 23.9 8.7 8.8 CGI_10015851 No 1 6 5.69 " IPR000408; Regulator of chromosome condensation, RCC1 IPR000433; Zinc finger, ZZ-type IPR000569; HECT IPR001199; Cytochrome b5 IPR004939; Anaphase-promoting complex, subunit 10, DOC domain IPR008979; Galactose-binding domain-like IPR009091; Regulator of chromosome condensation/beta-lactamase-inhibitor protein II IPR010606; Mib-herc2 IPR015940; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote IPR021097; CPH domain " PREDICTED: similar to hect domain and RLD 2 isoform 1 [Canis familiaris] 15.5 9.1 20.6 7.0 12.8 12.1 14.9 12.1 CGI_10014161 No 4 35 5.82 " IPR001254; Peptidase S1/S6, chymotrypsin/Hap IPR001314; Peptidase S1A, chymotrypsin-type IPR009003; Peptidase cysteine/serine, trypsin-like " RecName: Full=Chymotrypsin-like serine proteinase; Flags: Precursor emb|CAA50572.1| unnamed protein product [Haliotis rufescens] 0.1 0.2 0.0 0.1 4.2 0.0 0.1 28.0 CGI_10021115 No 1 4 5.85 IPR001315; Caspase Recruitment IPR011029; DEATH-like 1.3 1.8 5.3 0.1 1.3 148.2 1.2 1.2 CGI_10022792 Yes 1 2 5.87 " IPR003014; PAN-1 domain IPR013017; NHL repeat, subgroup IPR013602; Dynein heavy chain, N-terminal domain-2 " predicted protein [Nematostella vectensis] gb|EDO34077.1| predicted protein [Nematostella vectensis] 17.9 14.4 3.7 7.2 17.2 45.3 40.2 22.0 CGI_10013025 No 1 3 5.88 IPR000225; Armadillo IPR001107; Band 7 protein IPR013284; Beta-catenin IPR016024; Armadillo-type fold beta-catenin [Aplysia californica] gb|AAY29569.1| beta-catenin [Aplysia californica] 258.9 393.0 165.8 327.4 220.6 322.2 240.7 208.1 CGI_10007458 No 1 1 5.94 " IPR001148; Carbonic anhydrase, alpha-class, catalytic domain IPR019347; Axonemal dynein light chain " PREDICTED: similar to Uncharacterized protein C1orf125 homolog [Ciona intestinalis] 5.6 6.8 2.3 2.3 8.4 26.1 22.6 34.3 CGI_10010265 No 1 1 5.95 " IPR000315; Zinc finger, B-box IPR001258; NHL repeat IPR001841; Zinc finger, RING-type IPR013017; NHL repeat, subgroup IPR018957; Zinc finger, C3HC4 RING-type " hypothetical protein BRAFLDRAFT_85511 [Branchiostoma floridae] gb|EEN64934.1| hypothetical protein BRAFLDRAFT_85511 [Branchiostoma floridae] 4.6 13.1 0.8 0.6 10.4 19.5 17.3 7.7 CGI_10017545 Yes 16 228 5.96 " IPR000742; Epidermal growth factor-like, type 3 IPR001507; Endoglin/CD105 antigen IPR006210; Epidermal growth factor-like " RecName: Full=Gigasin-2; Flags: Precursor 31.5 0.0 0.5 0.0 1.9 0.2 0.0 13.9 CGI_10016965 No 14 112 5.96 " IPR003961; Fibronectin, type III IPR008957; Fibronectin type III domain " RecName: Full=Fibronectin type III domain-containing protein; AltName: Full=Fibronectin-like protein; Flags: Precursor 306.5 1.6 3.9 14.7 18.6 9.0 1.1 9.7 CGI_10009988 No 1 2 5.97 " IPR000719; Protein kinase, catalytic domain IPR001054; Adenylyl cyclase class-3/4/guanylyl cyclase IPR001245; Serine-threonine/tyrosine-protein kinase IPR011009; Protein kinase-like domain IPR020635; Tyrosine-protein kinase, catalytic domain " natriuretic peptide receptor B [Dasyatis sabina] 30.7 0.4 0.5 0.2 1.3 1.3 0.4 2.3 CGI_10015567 No 2 7 5.99 " IPR002223; Proteinase inhibitor I2, Kunitz metazoa " RecName: Full=Kunitz-type proteinase inhibitor 5 II; AltName: Full=SA5 II 19.7 0.0 0.0 0.7 1.1 0.2 0.0 2.0 CGI_10024919 No 1 1 6.00 " IPR003593; ATPase, AAA+ type, core IPR004273; Dynein heavy chain IPR013594; Dynein heavy chain, N-terminal domain-1 IPR013602; Dynein heavy chain, N-terminal domain-2 " hypothetical protein TRIADDRAFT_56463 [Trichoplax adhaerens] gb|EDV24554.1| hypothetical protein TRIADDRAFT_56463 [Trichoplax adhaerens] 3.6 6.3 1.1 1.2 5.8 24.8 19.7 17.9 CGI_10014639 No 1 1 6.01 IPR000198; Rho GTPase-activating protein domain IPR008936; Rho GTPase activation protein hypothetical protein DAPPUDRAFT_21313 [Daphnia pulex] 49.2 24.2 28.0 9.2 31.9 43.6 46.9 14.1 CGI_10013666 No 1 1 6.09 IPR006597; Sel1-like PREDICTED: predicted protein-like [Saccoglossus kowalevskii] 65.9 65.3 50.7 56.0 50.8 90.8 69.7 81.5 CGI_10016310 Yes 1 2 6.10 " IPR004843; Metallo-dependent phosphatase IPR006179; 5'-Nucleotidase/apyrase IPR008334; 5'-Nucleotidase, C-terminal " "PREDICTED: 5 nucleotidase, ecto-like [Saccoglossus kowalevskii]" 30.2 87.8 4.8 14.7 119.6 112.0 51.8 87.3 CGI_10022943 No 1 1 6.11 " IPR003126; Zinc finger, N-recognin IPR003769; Adaptor protein ClpS, core IPR013993; Zinc finger, N-recognin, metazoa IPR014719; Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like " hypothetical protein BRAFLDRAFT_227182 [Branchiostoma floridae] gb|EEN69419.1| hypothetical protein BRAFLDRAFT_227182 [Branchiostoma floridae] 13.5 12.0 61.1 9.8 11.5 11.8 13.3 13.0 CGI_10022573 No 1 2 6.18 23.6 6.7 1.2 1.4 8.7 32.6 36.2 9.9 CGI_10017711 No 1 2 6.23 " IPR000626; Ubiquitin IPR001841; Zinc finger, RING-type IPR001876; Zinc finger, RanBP2-type IPR019955; Ubiquitin supergroup " ubiquitin conjugating enzyme 7 interacting protein [Aedes aegypti] gb|EAT41367.1| ubiquitin conjugating enzyme 7 interacting protein [Aedes aegypti] 14.0 11.6 7.7 14.6 12.1 22.2 17.7 9.8 CGI_10009839 No 1 4 6.23 IPR000504; RNA recognition motif domain PREDICTED: similar to KIAA1839 protein [Gallus gallus] 5.5 10.0 5.6 6.2 6.4 5.5 7.5 6.5 CGI_10008472 No 1 3 6.24 IPR001715; Calponin homology domain PREDICTED: similar to cytospin A [Equus caballus] 41.5 33.2 20.2 62.4 39.2 34.8 45.1 40.3 CGI_10003780 No 1 1 6.24 " IPR011059; Metal-dependent hydrolase, composite domain IPR013108; Amidohydrolase 3 " urease domain protein [Microscilla marina ATCC 23134] gb|EAY29081.1| urease domain protein [Microscilla marina ATCC 23134] 0.3 0.3 0.0 0.1 0.1 1.3 0.2 0.5 CGI_10016219 No 1 1 6.25 IPR001849; Pleckstrin homology domain IPR004820; Cytidylyltransferase PREDICTED: similar to cholinephosphate cytidylyl transferase [Nasonia vitripennis] 78.6 54.8 41.2 66.3 56.3 55.2 86.4 75.0 CGI_10028384 No 1 2 6.25 " IPR005841; Alpha-D-phosphohexomutase IPR005843; Alpha-D-phosphohexomutase, C-terminal IPR005844; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I IPR005845; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II IPR005846; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III IPR016055; Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III " hypothetical protein BRAFLDRAFT_63910 [Branchiostoma floridae] gb|EEN67467.1| hypothetical protein BRAFLDRAFT_63910 [Branchiostoma floridae] 19.9 22.5 20.2 16.3 18.8 18.1 19.1 11.4 CGI_10027517 No 1 1 6.27 IPR003104; Actin-binding FH2/DRF autoregulatory IPR014768; GTPase-binding/formin homology 3 IPR015425; Actin-binding FH2 IPR016024; Armadillo-type fold PREDICTED: similar to CG32030 CG32030-PA [Tribolium castaneum] 75.5 25.2 405.7 8.7 29.3 49.8 49.1 32.3 CGI_10023552 No 1 2 6.32 " IPR003593; ATPase, AAA+ type, core IPR003959; ATPase, AAA-type, core IPR013718; COQ9 IPR013877; Uncharacterised protein family, YAP/Alf4/glomulin " PREDICTED: NAV2 protein-like [Saccoglossus kowalevskii] 22.4 13.5 20.5 13.4 16.2 15.6 16.7 11.4 CGI_10016397 No 10 136 6.37 " IPR001701; Glycoside hydrolase, family 9 IPR001841; Zinc finger, RING-type IPR001965; Zinc finger, PHD-type IPR002227; Tyrosinase IPR007110; Immunoglobulin-like IPR008922; Di-copper centre-containing IPR008928; Six-hairpin glycosidase-like IPR009071; High mobility group, superfamily IPR011011; Zinc finger, FYVE/PHD-type IPR019787; Zinc finger, PHD-finger " hypothetical protein TcasGA2_TC000606 [Tribolium castaneum] 19.6 19.7 23.1 13.8 49.6 25.8 24.4 23.2 CGI_10016964 Yes 22 213 6.43 " IPR003961; Fibronectin, type III IPR008957; Fibronectin type III domain " RecName: Full=Fibronectin type III domain-containing protein; AltName: Full=Fibronectin-like protein; Flags: Precursor 46.3 0.3 0.5 0.3 5.6 0.2 0.0 1.2 CGI_10007631 No 1 2 6.43 protein BRAFLDRAFT_122572 [Branchiostoma floridae] gb|EEN60722.1| hypothetical protein BRAFLDRAFT_122572 [Branchiostoma floridae] 12.1 12.5 8.1 3.9 9.8 55.2 35.1 113.6 CGI_10017338 No 1 3 6.46 IPR009976; Exocyst complex component Sec10 hypothetical protein BRAFLDRAFT_125658 [Branchiostoma floridae] gb|EEN66099.1| hypothetical protein BRAFLDRAFT_125658 [Branchiostoma floridae] 14.7 8.6 18.3 25.8 10.9 11.4 11.7 8.0 CGI_10005425 Yes 12 115 6.47 IPR001466; Beta-lactamase-related IPR012338; Beta-lactamase-type transpeptidase fold RecName: Full=Gigasin-6; Flags: Precursor 558.4 0.6 6.2 0.2 30.1 9.4 0.3 26.2 CGI_10023805 Yes 1 2 6.47 IPR001299; Ependymin expressed hypothetical protein [Trichoplax adhaerens] gb|EDV27620.1| expressed hypothetical protein [Trichoplax adhaerens] 390.8 457.0 142.1 375.4 404.6 530.2 655.4 348.2 CGI_10015381 Yes 2 4 6.49 " IPR001254; Peptidase S1/S6, chymotrypsin/Hap IPR001314; Peptidase S1A, chymotrypsin-type IPR009003; Peptidase cysteine/serine, trypsin-like " "hypothetical protein LOC574008 [Danio rerio] gb|AAH96885.1| Zgc:112302 [Danio rerio] emb|CAM56690.1| novel protein similar to vertebrate ELA1, Elastase-1 precursor, homolog (H.sapiens) (ELA1, zgc:112302) [Danio rerio]" 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.6 CGI_10006116 No 1 2 6.49 " IPR000315; Zinc finger, B-box " hypothetical protein BRAFLDRAFT_85511 [Branchiostoma floridae] gb|EEN64934.1| hypothetical protein BRAFLDRAFT_85511 [Branchiostoma floridae] 1.2 1.8 0.5 0.8 1.5 2.3 2.4 7.2 CGI_10014785 Yes 1 3 6.51 PREDICTED: UPF0462 protein C4orf33-like [Ailuropoda melanoleuca] 34.0 0.4 0.5 0.0 37.5 0.4 0.1 3.1 CGI_10020308 No 1 1 6.51 " IPR000337; GPCR, family 3 IPR017978; GPCR, family 3, C-terminal " PREDICTED: similar to metabotropic glutamate receptor type 3 (mGluR3) [Strongylocentrotus purpuratus] ref|XP_001194117.1| PREDICTED: similar to metabotropic glutamate receptor type 3 (mGluR3) [Strongylocentrotus purpuratus] 5.2 8.5 11.1 3.8 3.1 4.1 7.2 1.8 CGI_10013046 No 1 1 6.52 IPR002159; CD36 antigen IPR008081; Cytoplasmic FMR1-interacting cytoplasmic fragile X interacting protein [Aplysia californica] gb|AAU05773.1| cytoplasmic fragile X interacting protein [Aplysia californica] 44.1 18.6 15.0 13.9 25.9 41.9 44.1 16.8 CGI_10016430 No 2 17 6.54 67.2 0.0 0.4 0.0 3.2 0.0 0.0 0.5 CGI_10007514 Yes 7 45 6.58 IPR000566; Lipocalin/cytosolic fatty-acid binding protein IPR011038; Calycin-like "PREDICTED: similar to chlorophyllide A binding protein precursor, partial [Strongylocentrotus purpuratus]" 45.1 0.0 0.5 0.1 5.7 0.0 0.0 1.7 CGI_10007857 No 7 20 6.58 " IPR001540; Glycoside hydrolase, family 20 IPR008965; Carbohydrate-binding IPR015883; Glycoside hydrolase, family 20, catalytic core IPR017853; Glycoside hydrolase, catalytic core " beta-N-acetylhexosaminidase [Edwardsiella tarda EIB202] gb|ACY85446.1| beta-N-acetylhexosaminidase [Edwardsiella tarda EIB202] gb|ADM42455.1| Beta-hexosaminidase [Edwardsiella tarda FL6-60] 98.8 0.5 1.3 0.0 4.8 0.1 0.0 1.4 CGI_10017406 No 1 1 6.61 " IPR001251; Cellular retinaldehyde-binding/triple function, C-terminal IPR001936; Ras GTPase-activating protein IPR008936; Rho GTPase activation protein IPR016024; Armadillo-type fold " PREDICTED: similar to neurofibromin [Nasonia vitripennis] 21.1 20.3 13.1 8.5 23.1 29.8 22.7 20.1 CGI_10007021 No 5 27 6.64 " IPR001007; von Willebrand factor, type C IPR001734; Sodium/solute symporter IPR006552; VWC out " hypothetical protein BRAFLDRAFT_97142 [Branchiostoma floridae] gb|EEN51853.1| hypothetical protein BRAFLDRAFT_97142 [Branchiostoma floridae] 25.9 5.1 2.4 11.1 5.1 17.2 6.7 6.2 CGI_10008286 No 1 2 6.70 IPR019142; Dymeclin PREDICTED: CG8841-like [Saccoglossus kowalevskii] 20.1 16.7 14.8 19.1 15.0 22.8 19.9 17.2 CGI_10004269 No 1 1 6.70 " IPR000315; Zinc finger, B-box IPR013017; NHL repeat, subgroup " hypothetical protein BRAFLDRAFT_69798 [Branchiostoma floridae] gb|EEN63398.1| hypothetical protein BRAFLDRAFT_69798 [Branchiostoma floridae] 4.9 3.3 3.3 2.8 3.8 8.8 6.3 3.6 CGI_10006759 No 1 1 6.90 " IPR000536; Nuclear hormone receptor, ligand-binding, core IPR001628; Zinc finger, nuclear hormone receptor-type IPR001723; Steroid hormone receptor IPR008946; Nuclear hormone receptor, ligand-binding " nuclear receptor subfamily 1 ABC [Mytilus galloprovincialis] 56.4 37.0 55.7 84.5 36.0 59.1 58.0 30.5 CGI_10020492 No 1 1 6.90 IPR006652; Kelch repeat type 1 0.2 0.6 0.0 0.6 0.4 1.7 1.3 0.2 CGI_10018023 No 1 1 6.96 " IPR000830; Peripherin/rom-1 IPR008952; Tetraspanin, EC2 domain IPR018499; Tetraspanin " "novel protein similar to vertebrate retinal degeneration, slow protein (RDS) [Danio rerio]" 0.0 1.1 0.0 0.2 0.2 0.0 0.1 40.1 CGI_10005980 No 1 1 6.96 " IPR000192; Aminotransferase, class V/Cysteine desulfurase IPR011063; tRNA(Ile)-lysidine/2-thiocytidine synthase IPR015424; Pyridoxal phosphate-dependent transferase, major domain " predicted protein [Nematostella vectensis] gb|EDO49825.1| predicted protein [Nematostella vectensis] 9.3 13.8 16.8 12.1 7.5 8.4 8.8 7.4 CGI_10012899 No 1 2 7.03 " IPR000315; Zinc finger, B-box IPR001841; Zinc finger, RING-type " hypothetical protein BRAFLDRAFT_99625 [Branchiostoma floridae] gb|EEN56447.1| hypothetical protein BRAFLDRAFT_99625 [Branchiostoma floridae] 7.7 1.5 0.6 0.1 2.7 9.3 27.5 5.7 CGI_10006128 No 1 1 7.03 " IPR006925; Vps16, C-terminal IPR006926; Vps16, N-terminal IPR011046; WD40 repeat-like-containing domain " hypothetical protein BRAFLDRAFT_105238 [Branchiostoma floridae] gb|EEN47476.1| hypothetical protein BRAFLDRAFT_105238 [Branchiostoma floridae] 9.8 8.5 6.6 18.4 12.0 10.3 8.1 12.4 CGI_10018991 No 1 1 7.05 " IPR006628; PUR-alpha/beta/gamma, DNA/RNA-binding " "pur-alpha, putative [Ixodes scapularis] gb|EEC07044.1| pur-alpha, putative [Ixodes scapularis]" 50.6 37.2 60.2 75.1 35.9 32.7 37.0 68.0 CGI_10017543 Yes 12 153 7.08 " IPR000742; Epidermal growth factor-like, type 3 IPR001507; Endoglin/CD105 antigen IPR006210; Epidermal growth factor-like " RecName: Full=Gigasin-2; Flags: Precursor 121.3 0.4 1.2 1.4 7.0 3.4 0.0 7.6 CGI_10028414 No 3 5 7.11 " IPR001007; von Willebrand factor, type C IPR006552; VWC out IPR008037; Proteinase inhibitor I19, pacifastin " PREDICTED: mucin-2-like [Xenopus (Silurana) tropicalis] 28.6 0.0 0.3 0.4 0.8 0.5 0.1 3.6 CGI_10001200 No 1 4 7.12 " IPR001373; Cullin, N-terminal IPR016158; Cullin homology IPR016159; Cullin repeat-like-containing domain IPR019559; Cullin protein, neddylation domain " PREDICTED: cullin 5-like [Saccoglossus kowalevskii] 26.0 20.9 33.6 27.0 18.2 19.5 25.4 14.8 CGI_10011913 Yes 1 2 7.14 IPR002227; Tyrosinase IPR008922; Di-copper centre-containing tyrosinase precursor 2 [Illex argentinus] 182.2 0.1 1.5 0.0 7.8 0.1 0.0 0.4 CGI_10020105 No 1 1 7.17 " IPR002041; Ran GTPase IPR003577; Ras small GTPase, Ras type IPR003578; Small GTPase, Rho type IPR003579; Ras small GTPase, Rab type IPR013753; Ras " GTP-binding nuclear protein Ran [Anoplopoma fimbria] 1166.8 1485.6 1685.0 992.4 863.0 814.3 971.2 918.4 CGI_10002731 Yes 1 2 7.21 15.8 12.3 3.8 4.1 8.3 5.4 8.2 152.5 CGI_10019224 Yes 5 14 7.23 " IPR007117; Pollen allergen/expansin, C-terminal IPR009009; Barwin-related endoglucanase " predicted protein [Nematostella vectensis] gb|EDO38172.1| predicted protein [Nematostella vectensis] 0.1 0.2 0.0 0.2 0.5 0.0 0.4 0.3 CGI_10026852 No 1 1 7.27 " IPR015412; Autophagy-related, C-terminal " hypothetical protein BRAFLDRAFT_226506 [Branchiostoma floridae] gb|EEN59186.1| hypothetical protein BRAFLDRAFT_226506 [Branchiostoma floridae] 35.9 17.0 29.6 20.6 21.6 27.7 23.8 25.4 CGI_10020299 No 1 1 7.30 PREDICTED: novel NACHT domain containing protein-like [Danio rerio] 0.2 0.4 0.0 0.4 0.2 0.2 0.9 0.2 CGI_10010526 Yes 2 18 7.33 hypothetical protein TRIADDRAFT_32734 [Trichoplax adhaerens] gb|EDV19971.1| hypothetical protein TRIADDRAFT_32734 [Trichoplax adhaerens] 76.6 0.0 0.5 3.0 5.8 0.4 0.2 4.4 CGI_10026599 Yes 1 2 7.36 " IPR001223; Glycoside hydrolase, family 18, catalytic domain IPR011583; Chitinase II IPR017853; Glycoside hydrolase, catalytic core " Clp3 protein [Crassostrea gigas] 35.4 0.1 0.2 0.1 1.8 0.9 0.0 1.4 CGI_10008487 No 1 2 7.39 " IPR006090; Acyl-CoA oxidase/dehydrogenase, type 1 IPR006091; Acyl-CoA oxidase/dehydrogenase, central domain IPR006092; Acyl-CoA dehydrogenase, N-terminal IPR009075; Acyl-CoA dehydrogenase/oxidase C-terminal IPR009100; Acyl-CoA dehydrogenase/oxidase " PREDICTED: similar to glutaryl-Coenzyme A dehydrogenase [Strongylocentrotus purpuratus] ref|XP_001177809.1| PREDICTED: similar to glutaryl-Coenzyme A dehydrogenase [Strongylocentrotus purpuratus] 40.8 25.7 49.1 28.8 26.8 34.3 43.9 40.8 CGI_10002524 No 1 2 7.42 " IPR000323; Copper type II, ascorbate-dependent monooxygenase, N-terminal IPR008977; PHM/PNGase F-fold domain " temptin [Haliotis discus discus] 6.7 0.4 0.2 2.1 0.3 0.1 0.0 0.5 CGI_10019550 No 1 2 7.42 " IPR007087; Zinc finger, C2H2-type IPR015880; Zinc finger, C2H2-like IPR022755; Zinc finger, double-stranded RNA binding " PREDICTED: similar to mCG7830 [Acyrthosiphon pisum] 11.0 17.7 10.5 20.1 10.8 12.8 12.3 11.0 CGI_10008711 No 1 2 7.46 " IPR008972; Cupredoxin IPR011706; Multicopper oxidase, type 2 " hypothetical protein BRAFLDRAFT_206228 [Branchiostoma floridae] gb|EEN60772.1| hypothetical protein BRAFLDRAFT_206228 [Branchiostoma floridae] 31.9 0.0 0.1 0.0 3.3 0.0 0.0 0.8 CGI_10007002 No 1 1 7.46 " IPR002223; Proteinase inhibitor I2, Kunitz metazoa IPR008197; Whey acidic protein, 4-disulphide core " PREDICTED: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) isoform 2 [Bos taurus] ref|XP_002703617.1| PREDICTED: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) [Bos taurus] ref|XP_002685287.1| PREDICTED: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) isoform 1 [Bos taurus] ref|XP_002685288.1| PREDICTED: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) isoform 2 [Bos taurus] gb|DAA32850.1| tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) isoform 1 [Bos taurus] gb|DAA32851.1| tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) isoform 2 [Bos taurus] 20.3 0.0 0.0 0.0 0.4 0.1 0.0 1.7 CGI_10012419 No 1 1 7.47 130.1 1.2 1.4 0.2 5.3 4.9 1.8 10.0 CGI_10008469 No 1 1 7.55 Ceramide glucosyltransferase [Camponotus floridanus] 83.5 139.2 63.4 183.9 73.7 71.0 84.9 43.8 CGI_10002446 No 1 1 7.55 IPR018499; Tetraspanin "tetraspanin, putative [Aedes aegypti] ref|XP_001655058.1| tetraspanin, putative [Aedes aegypti] gb|EAT33414.1| tetraspanin, putative [Aedes aegypti] gb|EAT36983.1| tetraspanin, putative [Aedes aegypti]" 16.4 4.9 0.3 1.8 5.3 4.5 11.3 4.0 CGI_10009986 No 1 1 7.56 hypothetical protein BRAFLDRAFT_84494 [Branchiostoma floridae] gb|EEN69755.1| hypothetical protein BRAFLDRAFT_84494 [Branchiostoma floridae] 0.1 0.3 0.0 0.2 0.1 0.4 0.1 0.2 CGI_10019541 No 1 1 7.59 " IPR000342; Regulator of G protein signalling IPR001158; DIX IPR006145; Pseudouridine synthase, RsuA and RluB/C/D/E/F IPR014936; Axin beta-catenin binding IPR016137; Regulator of G protein signalling superfamily IPR020103; Pseudouridine synthase, catalytic domain " PREDICTED: similar to Axin isoform 1 [Monodelphis domestica] 13.9 39.1 14.5 26.2 26.0 16.5 13.9 15.0 CGI_10012743 No 15 87 7.64 IPR002227; Tyrosinase IPR008922; Di-copper centre-containing Tyrosinase-like protein tyr-1 [Ascaris suum] 116.8 0.7 1.4 0.1 8.4 3.5 0.0 14.1 CGI_10003700 No 1 1 7.64 " IPR000719; Protein kinase, catalytic domain IPR001245; Serine-threonine/tyrosine-protein kinase IPR002290; Serine/threonine-protein kinase domain IPR003306; WIF domain IPR011009; Protein kinase-like domain IPR020635; Tyrosine-protein kinase, catalytic domain " PREDICTED: similar to Tyrosine-protein kinase RYK [Gallus gallus] 16.4 7.6 15.4 12.7 16.4 28.8 21.4 14.7 CGI_10008375 No 7 101 7.66 IPR002110; Ankyrin repeat IPR020683; Ankyrin repeat-containing domain RecName: Full=Gigasin-4 7.6 3.8 0.3 0.2 3.8 3.2 5.0 3.4 CGI_10006717 No 1 3 7.74 " IPR001117; Multicopper oxidase, type 1 IPR008972; Cupredoxin IPR011707; Multicopper oxidase, type 3 " hypothetical protein BRAFLDRAFT_206228 [Branchiostoma floridae] gb|EEN60772.1| hypothetical protein BRAFLDRAFT_206228 [Branchiostoma floridae] 2.8 0.0 0.0 0.0 0.3 1.1 0.0 0.4 CGI_10026882 No 1 3 7.75 " IPR002181; Fibrinogen, alpha/beta/gamma chain, C-terminal globular " PREDICTED: microfibrillar-associated protein 4-like [Bos taurus] gb|DAA24205.1| microfibrillar-associated protein 4-like [Bos taurus] 2.6 0.2 0.0 0.1 0.2 0.1 0.0 0.1 CGI_10005424 No 1 18 7.77 IPR001466; Beta-lactamase-related IPR012338; Beta-lactamase-type transpeptidase fold RecName: Full=Gigasin-6; Flags: Precursor 365.0 0.4 3.2 0.3 17.4 4.2 0.0 8.0 CGI_10023851 No 7 83 7.77 " IPR002130; Peptidyl-prolyl cis-trans isomerase, cyclophilin-type IPR015891; Cyclophilin-like " cyclophilin B [Ictalurus punctatus] gb|ABC75555.1| peptidylprolyl isomerase B [Ictalurus punctatus] gb|ABO15710.1| cyclophilin B [Ictalurus punctatus] 160.1 3.2 5.8 15.2 10.4 5.2 1.2 21.0 CGI_10027222 Yes 1 2 7.78 IPR001023; Heat shock protein Hsp70 IPR013126; Heat shock protein 70 predicted protein [Nematostella vectensis] gb|EDO40250.1| predicted protein [Nematostella vectensis] 2.5 4.5 1.7 7.4 3.2 4.9 2.9 6.0 CGI_10015796 No 1 1 7.83 IPR001054; Adenylyl cyclase class-3/4/guanylyl cyclase IPR011645; Haem NO binding associated IPR013587; Nitrate/nitrite sensing protein PREDICTED: guanylate cyclase 2G-like [Saccoglossus kowalevskii] 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.2 CGI_10007232 No 1 1 7.84 hypothetical protein BRAFLDRAFT_146669 [Branchiostoma floridae] gb|EEN59680.1| hypothetical protein BRAFLDRAFT_146669 [Branchiostoma floridae] 28.3 59.3 43.3 56.9 32.1 27.2 25.7 37.8 CGI_10009993 No 1 1 7.87 IPR001357; BRCT PREDICTED: hypothetical protein LOC100398140 [Callithrix jacchus] 11.8 21.8 21.6 17.3 12.1 13.4 13.8 20.5 CGI_10017426 No 5 27 7.87 " IPR002007; Haem peroxidase, animal IPR010255; Haem peroxidase IPR019791; Haem peroxidase, animal, subgroup " peroxinectin [Pacifastacus leniusculus] 4.3 0.2 0.2 1.1 0.5 2.2 0.2 1.1 CGI_10028037 No 1 1 7.88 200.8 0.8 1.6 0.0 6.5 0.0 0.0 0.4 CGI_10007411 No 1 2 7.90 36.6 18.0 1.9 2.5 4.4 1.8 1.3 5.1 CGI_10028495 No 2 3 7.96 " IPR001148; Carbonic anhydrase, alpha-class, catalytic domain " RecName: Full=Nacrein-like protein 18.2 1.6 0.5 0.6 3.8 4.1 0.5 42.0 CGI_10001495 No 1 1 7.96 IPR006029; Neurotransmitter-gated ion-channel transmembrane domain IPR006201; Neurotransmitter-gated ion-channel IPR006202; Neurotransmitter-gated ion-channel ligand-binding "cholinergic receptor, nicotinic, beta polypeptide 3a [Danio rerio] gb|AAP14898.1| neuronal nicotinic acetylcholine receptor beta 3 subunit [Danio rerio] gb|AAI62137.1| Cholinergic receptor, nicotinic, beta polypeptide 3a [Danio rerio] gb|AAI62133.1| Cholinergic receptor, nicotinic, beta polypeptide 3a [Danio rerio]" 0.2 1.5 0.0 0.0 0.6 0.0 0.0 0.1 CGI_10008103 No 1 1 7.96 " IPR001214; SET domain IPR001965; Zinc finger, PHD-type IPR003616; Post-SET domain IPR003888; FY-rich, N-terminal IPR003889; FY-rich, C-terminal IPR011011; Zinc finger, FYVE/PHD-type IPR017956; AT hook, DNA-binding motif IPR018516; FY-rich, C-terminal subgroup IPR018518; FY-rich, N-terminal subgroup IPR019787; Zinc finger, PHD-finger IPR020478; AT hook-like " PREDICTED: similar to MLL protein [Gallus gallus] 15.2 15.9 14.3 14.1 14.1 14.0 15.9 9.2 CGI_10006035 No 1 1 7.96 " IPR001650; Helicase, C-terminal IPR007502; Helicase-associated domain IPR011545; DNA/RNA helicase, DEAD/DEAH box type, N-terminal IPR011709; Domain of unknown function DUF1605 IPR014001; DEAD-like helicase, N-terminal IPR014021; Helicase, superfamily 1/2, ATP-binding domain " predicted protein [Nematostella vectensis] gb|EDO43167.1| predicted protein [Nematostella vectensis] 3.7 5.7 4.2 4.8 4.9 4.9 5.3 5.6 CGI_10026605 Yes 2 11 7.97 " IPR001223; Glycoside hydrolase, family 18, catalytic domain IPR002557; Chitin binding domain IPR011583; Chitinase II IPR017853; Glycoside hydrolase, catalytic core " Chit3 protein [Crassostrea gigas] 123.2 0.4 1.0 0.1 6.6 3.5 0.2 11.6 CGI_10028286 No 3 7 7.97 " IPR006150; Cysteine-rich repeat IPR008037; Proteinase inhibitor I19, pacifastin " hypothetical protein sce4104 [Sorangium cellulosum 'So ce 56'] emb|CAN94267.1| Hypothetical protein sce4104 [Sorangium cellulosum 'So ce 56'] 169.2 0.2 2.6 0.2 10.1 2.2 0.0 3.6 CGI_10007670 Yes 3 7 8.00 178.0 0.0 1.8 0.2 24.7 0.4 0.0 0.9 CGI_10008969 Yes 3 18 8.03 " IPR001117; Multicopper oxidase, type 1 IPR008972; Cupredoxin IPR011706; Multicopper oxidase, type 2 IPR011707; Multicopper oxidase, type 3 " Laccase [Harpegnathos saltator] 16.8 7.7 5.9 0.8 8.7 8.5 11.6 27.9 CGI_10017433 No 1 2 8.05 hypothetical protein BRAFLDRAFT_76554 [Branchiostoma floridae] gb|EEN46312.1| hypothetical protein BRAFLDRAFT_76554 [Branchiostoma floridae] 0.2 0.5 0.8 0.0 0.0 0.0 0.3 0.0 CGI_10009952 No 1 1 8.09 " IPR001506; Peptidase M12A, astacin IPR003582; Metridin-like ShK toxin IPR006026; Peptidase, metallopeptidase " astacin-like protein [Pinctada fucata] 7.5 2.6 8.6 0.6 3.5 71.9 4.4 0.6 CGI_10013045 No 1 1 8.10 " IPR006621; Nose resistant-to-fluoxetine protein, N-terminal " hypothetical protein BRAFLDRAFT_66621 [Branchiostoma floridae] gb|EEN56124.1| hypothetical protein BRAFLDRAFT_66621 [Branchiostoma floridae] 0.5 15.4 1.3 1.8 23.5 0.0 0.4 1.5 CGI_10015860 No 1 1 8.10 " IPR000560; Histidine phosphatase superfamily, clade-2 " PREDICTED: similar to conserved hypothetical protein [Nasonia vitripennis] 21.8 17.3 26.7 16.5 19.9 19.0 25.8 30.9 CGI_10011916 No 2 3 8.18 IPR002227; Tyrosinase IPR008922; Di-copper centre-containing tyrosinase [Sepia officinalis] 222.0 0.8 1.6 0.0 13.0 1.9 0.0 4.7 CGI_10020818 No 1 6 8.18 " IPR002223; Proteinase inhibitor I2, Kunitz metazoa " PREDICTED: im:7152043 [Danio rerio] 0.2 0.8 0.0 0.4 0.0 0.2 0.6 0.5 CGI_10022480 No 3 7 8.18 IPR001283; Allergen V5/Tpx-1-related IPR002413; Ves allergen IPR014044; CAP domain GLI pathogenesis-related 1 like 1 [Mus musculus] dbj|BAB24280.1| unnamed protein product [Mus musculus] 0.3 0.0 0.2 0.2 0.0 0.0 0.1 0.1 CGI_10016329 No 1 1 8.27 " IPR002575; Aminoglycoside phosphotransferase IPR005833; Haloacid dehydrogenase/epoxide hydrolase IPR005834; Haloacid dehalogenase-like hydrolase IPR006090; Acyl-CoA oxidase/dehydrogenase, type 1 IPR006091; Acyl-CoA oxidase/dehydrogenase, central domain IPR006092; Acyl-CoA dehydrogenase, N-terminal IPR009075; Acyl-CoA dehydrogenase/oxidase C-terminal IPR009100; Acyl-CoA dehydrogenase/oxidase IPR011009; Protein kinase-like domain IPR023214; HAD-like domain " PREDICTED: predicted protein-like [Saccoglossus kowalevskii] 25.0 33.2 20.1 20.1 51.4 27.5 25.5 14.8 CGI_10016999 No 1 2 8.32 " IPR001590; Peptidase M12B, ADAM/reprolysin " hypothetical protein BRAFLDRAFT_95556 [Branchiostoma floridae] gb|EEN55878.1| hypothetical protein BRAFLDRAFT_95556 [Branchiostoma floridae] 80.8 0.2 0.9 0.1 5.2 2.3 0.1 2.4 CGI_10018402 No 1 3 8.38 " IPR000212; DNA helicase, UvrD/REP type " hypothetical protein AND_08491 [Anopheles darlingi] 43.6 29.0 30.4 35.8 33.6 37.5 35.5 35.6 CGI_10000983 No 1 4 8.38 IPR001073; Complement C1q protein IPR008983; Tumour necrosis factor-like putative C1q domain containing protein MgC1q26 [Mytilus galloprovincialis] 100.9 11.9 44.2 314.0 36.7 42.7 48.5 11.0 CGI_10005749 Yes 4 29 8.41 RecName: Full=Gigasin-3a 30.4 0.6 0.7 0.2 2.4 0.4 0.0 12.0 CGI_10015700 No 1 1 8.44 " IPR002035; von Willebrand factor, type A IPR006587; Vault protein inter-alpha-trypsin, metazoa IPR013694; Vault protein inter-alpha-trypsin " hypothetical protein DAPPUDRAFT_221972 [Daphnia pulex] 313.6 134.9 66.4 205.1 123.9 138.2 116.6 245.7 CGI_10008228 No 2 5 8.44 "transmembrane protein 145, isoform CRA_b [Mus musculus]" 94.9 39.1 16.6 159.6 44.1 100.6 99.1 37.2 CGI_10024501 No 2 5 8.47 " IPR000194; ATPase, alpha/beta subunit, nucleotide-binding domain IPR000793; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal IPR004100; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal IPR018118; ATPase, F1/A1 complex, alpha/beta subunit, N-terminal " mitochondrial H+ ATPase a subunit [Pinctada fucata] 231.5 257.3 350.0 168.3 188.7 210.6 182.9 353.8 CGI_10016959 No 1 1 8.47 IPR003172; MD-2-related lipid-recognition IPR014756; Immunoglobulin E-set Epididymal secretory protein E1 precursor [Anoplopoma fimbria] 11.6 12.9 6.8 13.5 183.5 11.5 9.7 19.8 CGI_10023176 No 1 1 8.47 0.0 0.2 0.0 0.0 0.0 0.0 0.0 109.0 CGI_10019123 No 1 1 8.50 IPR005821; Ion transport U-type voltage-gated cation channel alpha-1 subunit isoform A [Lymnaea stagnalis] 16.4 12.5 18.6 10.5 10.9 13.0 14.0 9.2 CGI_10024410 Yes 1 2 8.51 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 CGI_10020232 No 1 3 8.59 " IPR002035; von Willebrand factor, type A " PREDICTED: collagen alpha-6(VI) chain-like [Xenopus (Silurana) tropicalis] 33.2 2.0 2.8 0.4 2.4 13.9 4.3 7.6 CGI_10026879 No 1 2 8.60 " IPR002181; Fibrinogen, alpha/beta/gamma chain, C-terminal globular " PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] ref|XP_001182824.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] 0.7 0.0 0.0 0.0 0.1 1.0 0.0 0.3 CGI_10018988 No 1 2 8.60 12.9 0.2 0.3 0.2 1.2 0.2 0.4 1.1 CGI_10014272 No 1 3 8.65 Round spermatid basic protein 1-like protein [Harpegnathos saltator] 10.5 14.9 12.1 12.4 10.5 15.0 12.7 14.0 CGI_10017087 No 3 15 8.69 IPR002557; Chitin binding domain 72.3 0.7 0.6 0.0 5.7 2.4 0.1 6.0 CGI_10009105 No 1 2 8.76 " IPR000742; Epidermal growth factor-like, type 3 IPR000884; Thrombospondin, type 1 repeat IPR003129; Laminin G, thrombospondin-type, N-terminal IPR006210; Epidermal growth factor-like IPR008985; Concanavalin A-like lectin/glucanase IPR008993; Tissue inhibitor of metalloproteinases-like, OB-fold IPR012680; Laminin G, subdomain 2 IPR013111; EGF, extracellular " PREDICTED: similar to TFP250 [Strongylocentrotus purpuratus] ref|XP_001180512.1| PREDICTED: similar to TFP250 [Strongylocentrotus purpuratus] 2.7 1.0 0.5 0.2 1.2 2.1 5.6 1.9 CGI_10017085 No 1 1 8.88 hypothetical protein BRAFLDRAFT_90331 [Branchiostoma floridae] gb|EEN41932.1| hypothetical protein BRAFLDRAFT_90331 [Branchiostoma floridae] 13.6 0.0 0.0 0.0 1.1 0.6 0.0 1.8 CGI_10022355 No 1 1 8.94 IPR003598; Immunoglobulin subtype 2 IPR003599; Immunoglobulin subtype IPR007110; Immunoglobulin-like IPR013098; Immunoglobulin I-set IPR022189; Smoothelin cytoskeleton protein PREDICTED: connectin/titin-like [Saccoglossus kowalevskii] 35.2 18.6 104.8 8.5 34.6 61.9 25.4 19.2 CGI_10020828 No 1 2 8.97 " IPR002223; Proteinase inhibitor I2, Kunitz metazoa " C. briggsae CBR-MEC-1 protein [Caenorhabditis briggsae] 0.3 0.1 0.3 0.2 0.0 0.3 0.7 0.2 CGI_10008376 No 7 74 9.00 RecName: Full=Gigasin-4 177.0 0.2 1.5 0.0 6.4 0.1 0.0 1.2 CGI_10002204 No 1 9 9.06 IPR001453; Molybdopterin binding 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CGI_10007753 No 2 4 9.11 IPR002227; Tyrosinase IPR008922; Di-copper centre-containing tyrosinase [Sepia officinalis] 136.9 1.4 1.2 0.3 7.6 0.3 0.0 0.7 CGI_10005529 No 1 7 9.11 " IPR000421; Coagulation factor 5/8 type, C-terminal IPR000859; CUB IPR001304; C-type lectin IPR006585; Fucolectin tachylectin-4 pentraxin-1 IPR008979; Galactose-binding domain-like IPR016187; C-type lectin fold " bindin precursor 4 repeat variant [Crassostrea gigas] 0.0 0.7 0.0 0.1 0.5 0.0 0.0 1809.1 CGI_10018175 No 2 7 9.19 110.0 5.0 1.9 0.0 9.2 5.1 0.0 13.6 CGI_10019576 No 1 1 9.23 IPR012816; Conserved hypothetical protein CHP02464 PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] ref|XP_001195388.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] 6.0 3.6 1.8 7.5 4.8 5.9 9.8 6.6 CGI_10016966 No 2 3 9.31 " IPR003961; Fibronectin, type III IPR008957; Fibronectin type III domain " receptor tyrosine phosphatase [Hirudo medicinalis] 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.2 CGI_10007922 No 1 1 9.31 113.3 54.3 128.0 150.9 66.9 134.5 113.7 102.6 CGI_10009634 No 2 6 9.31 434.2 0.1 4.3 0.0 29.5 0.2 0.0 0.7 CGI_10007669 No 2 9 9.32 79.9 0.7 1.3 0.2 11.1 0.0 0.2 0.1 CGI_10021817 Yes 2 6 9.35 " IPR001747; Lipid transport protein, N-terminal IPR001846; von Willebrand factor, type D domain IPR015255; Vitellinogen, open beta-sheet IPR015819; Lipid transport protein, beta-sheet shell " vitellogenin [Crassostrea gigas] 0.5 1857.7 2.7 3.8 402.4 0.0 0.3 0.7 CGI_10012474 No 2 5 9.35 " IPR000795; Protein synthesis factor, GTP-binding IPR004160; Translation elongation factor EFTu/EF1A, C-terminal IPR004161; Translation elongation factor EFTu/EF1A, domain 2 IPR009000; Translation elongation/initiation factor/Ribosomal, beta-barrel IPR009001; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal " elongation factor 1 alpha [Crassostrea gigas] 9826.1 8199.6 7250.2 5400.3 7751.7 6053.7 7017.5 5439.4 CGI_10023928 No 2 3 9.39 " IPR000172; Glucose-methanol-choline oxidoreductase, N-terminal IPR007867; Glucose-methanol-choline oxidoreductase, C-terminal " PREDICTED: similar to ENSANGP00000015190 [Nasonia vitripennis] 38.3 0.5 0.5 0.0 2.1 1.5 0.1 3.7 CGI_10004704 No 6 24 9.41 " IPR008197; Whey acidic protein, 4-disulphide core " translation initiation factor IF-2 [Clostridium papyrosolvens DSM 2782] gb|EEU58569.1| translation initiation factor IF-2 [Clostridium papyrosolvens DSM 2782] 15.9 0.0 0.2 0.0 1.3 0.2 0.1 0.5 CGI_10022840 No 4 12 9.50 16.7 0.2 0.2 0.0 0.9 0.0 0.0 0.1 CGI_10016030 No 1 2 9.55 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.8 CGI_10005694 No 1 1 9.58 " IPR001320; Ionotropic glutamate receptor IPR001508; NMDA receptor IPR001638; Extracellular solute-binding protein, family 3 IPR001828; Extracellular ligand-binding receptor " glutamate receptor subunit protein GluR2 [Aplysia californica] gb|AAP41204.1| glutamate receptor subunit protein GluR2 [Aplysia californica] 1.0 2.2 5.4 0.2 0.9 1.6 0.3 0.9 CGI_10005220 Yes 1 4 9.63 IPR001073; Complement C1q protein IPR008983; Tumour necrosis factor-like putative C1q domain containing protein MgC1q52 [Mytilus galloprovincialis] 69.7 0.6 0.3 0.2 3.9 1.0 0.5 0.8 CGI_10028183 No 1 1 9.64 " IPR000048; IQ motif, EF-hand binding site IPR001609; Myosin head, motor domain IPR010926; Myosin tail 2 " predicted protein [Nematostella vectensis] gb|EDO49515.1| predicted protein [Nematostella vectensis] 45.2 20.3 21.1 9.0 24.6 33.0 40.3 17.9 CGI_10011406 No 1 1 9.67 " IPR000276; 7TM GPCR, rhodopsin-like IPR017452; GPCR, rhodopsin-like superfamily " neuropeptide Y [Haliotis discus hannai] 5.0 4.8 2.4 27.7 7.9 7.1 7.2 3.6 CGI_10027846 No 1 4 9.69 IPR004344; Tubulin-tyrosine ligase hypothetical protein BRAFLDRAFT_223430 [Branchiostoma floridae] gb|EEN47629.1| hypothetical protein BRAFLDRAFT_223430 [Branchiostoma floridae] 8.6 6.5 1.2 2.0 12.5 29.4 29.5 73.5 CGI_10015115 No 1 1 9.69 predicted protein [Nematostella vectensis] gb|EDO42197.1| predicted protein [Nematostella vectensis] 7.2 8.3 0.8 0.5 16.2 38.2 36.5 125.9 CGI_10013423 No 1 1 9.70 IPR003121; SWIB/MDM2 domain IPR019835; SWIB domain "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 [Xenopus (Silurana) tropicalis]" 22.2 40.7 37.7 41.9 21.8 33.3 20.5 28.2 CGI_10024148 No 1 1 9.72 IPR000182; GCN5-related N-acetyltransferase (GNAT) domain IPR013110; Histone methylation DOT1 IPR016181; Acyl-CoA N-acyltransferase PREDICTED: similar to histone h3 methyltransferase [Tribolium castaneum] gb|EFA11417.1| hypothetical protein TcasGA2_TC013593 [Tribolium castaneum] 24.3 31.4 15.4 42.6 40.2 30.5 27.8 32.6 CGI_10023977 No 1 1 9.72 IPR005612; CCAAT-binding factor IPR011501; Nucleolar complex-associated IPR016024; Armadillo-type fold PREDICTED: similar to AD24 protein [Gallus gallus] 8.8 19.8 21.3 11.1 10.8 8.8 8.2 24.7 CGI_10019762 No 1 1 9.76 1.9 1.5 0.0 0.2 0.6 0.9 0.4 2.1 CGI_10024155 No 1 1 9.80 8.0 15.3 1.1 0.2 10.6 15.5 41.4 12.4 CGI_10024306 No 1 1 9.82 IPR000595; Cyclic nucleotide-binding domain IPR018490; Cyclic nucleotide-binding-like "PREDICTED: protein kinase, cGMP-dependent, type II-like [Saccoglossus kowalevskii]" 0.9 5.2 0.6 0.4 10.2 6.5 29.0 14.7 CGI_10012913 No 1 1 9.83 " IPR007087; Zinc finger, C2H2-type IPR015880; Zinc finger, C2H2-like " PREDICTED: zinc finger protein 197-like [Danio rerio] 8.0 3.7 8.0 1.6 9.2 3.6 16.0 7.6 CGI_10002978 No 1 1 9.92 0.1 0.7 0.2 0.1 0.4 0.2 0.9 0.1 CGI_10005981 No 1 1 9.95 " IPR007823; Methyltransferase-related IPR010456; Ribosomal L11 methyltransferase, PrmA " hypothetical protein TcasGA2_TC000195 [Tribolium castaneum] 1.1 6.7 4.4 3.8 2.8 1.6 1.5 10.7 CGI_10014006 No 1 1 9.96 PREDICTED: predicted protein-like [Saccoglossus kowalevskii] 2.1 3.1 0.6 0.2 7.3 13.7 10.2 96.0 CGI_10023850 Yes 1 1 9.98 " IPR002130; Peptidyl-prolyl cis-trans isomerase, cyclophilin-type IPR015891; Cyclophilin-like " Peptidyl-prolyl cis-trans isomerase B [Ascaris suum] 22.1 22.8 131.3 26.1 14.7 13.9 9.5 11.7 CGI_10024229 No 9 128 9.98 118.6 0.9 1.7 0.0 9.5 3.8 0.1 37.2 CGI_10022652 No 1 1 9.99 2.6 0.0 0.2 1.7 0.6 4.9 3.3 1.5 CGI_10013329 No 1 3 10.01 " IPR001128; Cytochrome P450 IPR002401; Cytochrome P450, E-class, group I " CYP356A1 [Crassostrea gigas] 2.1 6.1 0.2 1.0 3.0 1.9 2.1 1.8 CGI_10013462 Yes 3 7 10.05 " IPR004302; Chitin-binding, domain 3 " "PREDICTED: similar to CG15786 CG15786-PA, partial [Ciona intestinalis]" 2.4 0.2 0.0 0.2 0.5 0.7 0.4 1.3 CGI_10018173 No 2 2 10.08 hypothetical protein AURANDRAFT_65843 [Aureococcus anophagefferens] 34.2 0.1 0.5 0.0 2.7 0.4 0.0 5.5 CGI_10016968 No 1 6 10.13 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 CGI_10018176 Yes 3 19 10.17 GE25081 [Drosophila yakuba] gb|EDW96121.1| GE25081 [Drosophila yakuba] 85.7 4.0 1.0 0.0 7.1 3.7 0.0 5.7 CGI_10014371 No 1 1 10.17 " IPR016027; Nucleic acid-binding, OB-fold-like " 0.2 0.4 0.9 0.5 1.0 0.0 0.3 0.1 CGI_10005096 No 4 33 10.18 " IPR008197; Whey acidic protein, 4-disulphide core " PREDICTED: similar to 63 kD protein [Strongylocentrotus purpuratus] ref|XP_001190360.1| PREDICTED: similar to 63 kD protein [Strongylocentrotus purpuratus] 90.9 0.3 0.8 0.2 6.6 2.2 0.0 8.1 CGI_10002486 No 1 2 10.23 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CGI_10025732 No 1 1 10.24 PREDICTED: telomerase-associated protein 1-like [Saccoglossus kowalevskii] 5.4 25.7 3.5 3.3 12.6 22.0 26.5 14.2 CGI_10011015 Yes 1 1 10.33 " IPR001820; Proteinase inhibitor I35, tissue inhibitor of metalloproteinase IPR008993; Tissue inhibitor of metalloproteinases-like, OB-fold " 38.3 0.0 0.2 0.4 1.3 0.5 0.0 0.2 CGI_10008434 No 8 25 10.37 PREDICTED: neurogenic locus notch homolog protein 2-like [Saccoglossus kowalevskii] 93.7 0.1 1.0 0.0 6.8 1.0 0.0 0.8 CGI_10004228 Yes 2 4 10.42 hypothetical protein EAG_13268 [Camponotus floridanus] 131.4 0.1 1.9 0.0 7.3 3.1 0.1 7.2 CGI_10001873 No 1 2 10.45 2.0 1.6 0.0 0.1 5.9 6.0 15.0 1.9 CGI_10020756 No 5 63 10.68 " IPR002223; Proteinase inhibitor I2, Kunitz metazoa " single Kunitz protease inhibitor 2 [Simulium nigrimanum] 6.2 0.6 0.0 0.0 0.7 0.0 0.0 0.9 CGI_10017398 No 1 2 10.70 102.5 0.2 0.8 0.3 8.7 1.2 0.0 12.4 CGI_10027091 No 2 17 10.77 20.8 0.2 0.2 0.0 1.5 0.1 0.0 0.2 CGI_10016624 No 1 1 10.81 IPR000218; Ribosomal protein L14b/L23e "39S ribosomal protein L14, mitochondrial [Culex quinquefasciatus] gb|EDS30229.1| 39S ribosomal protein L14, mitochondrial [Culex quinquefasciatus]" 15.0 51.3 42.4 18.8 22.0 22.5 14.6 11.7 CGI_10023446 No 2 6 10.86 484.5 0.3 5.4 0.0 38.3 8.3 0.8 74.4 CGI_10004227 No 15 113 11.08 210.3 0.2 2.9 0.1 13.2 5.6 0.0 13.2 CGI_10004954 No 1 2 11.11 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CGI_10010378 No 1 2 12.09 IPR000253; Forkhead-associated (FHA) domain IPR008984; SMAD/FHA domain PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] ref|XP_001185951.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] 10.1 196.2 18.5 105.8 43.8 18.3 11.0 155.5 "Note: * ""NA"" indicates that the protein is not secreted protein. The pI was calculated at http://web.expasy.org/compute_pi/ "