circ (583,473) 4	/dbget-bin/www_bget?C00533	C00533 (Nitric oxide)
circ (398,230) 4	/dbget-bin/www_bget?C00076	C00076 (Calcium cation)
circ (343,230) 4	/dbget-bin/www_bget?C01245	C01245 (D-myo-Inositol 1,4,5-trisphosphate)
circ (342,178) 4	/dbget-bin/www_bget?C00165	C00165 (Diacylglycerol)
circ (341,439) 4	/dbget-bin/www_bget?C05981	C05981 (Phosphatidylinositol-3,4,5-trisphosphate)
circ (905,251) 4	/dbget-bin/www_bget?C01312	C01312 (Prostaglandin I2)
rect (278,340) (324,357)	/dbget-bin/www_bget?hsa:998	998 (CDC42)
rect (120,301) (166,318)	/dbget-bin/www_bget?hsa:3791+D03218+D05029+D05380+D05819+D06272+D06285+D06402+D06407+D06678+D08524+D08552+D08883+D08947	3791 (KDR), D03218 (Axitinib (JAN/USAN)), D05029 (Midostaurin (USAN/INN)), D05380 (Pazopanib hydrochloride (JAN/USAN)), D05819 (Semaxanib (USAN/INN)), D06272 (Sorafenib tosilate (JAN)), D06285 (Vatalanib (USAN/INN)), D06402 (Sunitinib malate (JAN/USAN)), D06407 (Vandetanib (JAN/USAN/INN)), D06678 (Motesanib), D08524 (Sorafenib (USAN/INN)), D08552 (Sunitinib (INN)), D08883 (Cediranib maleate (JAN/USAN)), D08947 (Motesanib diphosphate (USAN))
rect (247,221) (293,238)	/dbget-bin/www_bget?hsa:5335+hsa:5336	5335 (PLCG1), 5336 (PLCG2)
rect (483,108) (529,125)	/dbget-bin/www_bget?hsa:56848+hsa:8877	56848 (SPHK2), 8877 (SPHK1)
rect (726,222) (772,239)	/dbget-bin/www_bget?hsa:5743+H00017+H00025+H00046+D00109+D00118+D00120+D00126+D00127+D00130+D00132+D00141+D00151+D00158+D00169+D00315+D00330+D00425+D00428+D00448+D00463+D00510+D00566+D00567+D00568+D00810+D00813+D00827+D00903+D00904+D00968+D00969+D00970+D01049+D01122+D01183+D01267+D01325+D01397+D01410+D01475+D01513+D01547+D01565+D01578+D01581+D01582+D01709+D01765+D01767+D01788+D01811+D01866+D01974+D02110+D02290+D02341+D02350+D02355+D02709+D03254+D03410+D03652+D03689+D03710+D03712+D03714+D03715+D03716+D03717+D03718+D04490+D05181+D05511+D05512+D05513+D06606+D07269+D07421+D07443+D07516+D07517+D07579+D07580+D07581+D07582+D07816+D07817+D07818+D07819+D08058+D08059+D08102+D08103+D08104+D08149+D08363+D08364+D08374+D08375+D08427+D09760	5743 (PTGS2), H00017 (Esophageal cancer), H00025 (Penile cancer), H00046 (Cholangiocarcinoma), D00109 (Aspirin (JP16/USP)), D00118 (Naproxen (JP16/USP/INN)), D00120 (Sulindac (JP16/USP/INN)), D00126 (Ibuprofen (JP16/USP/INN)), D00127 (Piroxicam (JP16/USP/INN)), D00130 (Diflunisal (JAN/USP/INN)), D00132 (Ketoprofen (JP16/USP/INN)), D00141 (Indometacin (JP16/INN)), D00151 (Mefenamic acid (JP16/USP/INN)), D00158 (Tolmetin sodium (JAN/USP)), D00169 (Meclofenamate sodium (USP)), D00315 (Etodolac (JP16/USP/INN)), D00330 (Flurbiprofen (JP16/USP/INN)), D00425 (Nabumetone (JP16/USP/INN)), D00428 (Sasapyrine (JAN)), D00448 (Salazosulfapyridine (JP16)), D00463 (Oxaprozin (JP16/USAN/INN)), D00510 (Phenylbutazone (JP16/USP/INN)), D00566 (Sodium salicylate (JP16/USP)), D00567 (Celecoxib (JAN/USAN/INN)), D00568 (Rofecoxib (JAN/USAN/INN)), D00810 (Choline salicylate (JAN/USAN/INN)), D00813 (Ketorolac tromethamine (USP)), D00827 (Magnesium salicylate (USP)), D00903 (Diclofenac potassium (USAN)), D00904 (Diclofenac sodium (JP16/USP)), D00968 (Fenoprofen calcium (JAN/USP)), D00969 (Meloxicam (JAN/USAN/INN)), D00970 (Naproxen sodium (USP)), D01049 (Nimesulide (JAN/INN)), D01122 (Ibuprofen piconol (JAN/USAN)), D01183 (Tolfenamic acid (JAN/INN)), D01267 (Floctafenine (JAN/USAN/INN)), D01325 (Tiaprofenic acid (JAN/INN)), D01397 (Ampiroxicam (JAN/INN)), D01410 (Benzydamine hydrochloride (JAN/USAN)), D01475 (Flurbiprofen axetil (JAN)), D01513 (Alminoprofen (JP16/INN)), D01547 (Zaltoprofen (JP16/INN)), D01565 (Indometacin farnesil (JAN)), D01578 (Pranoprofen (JP16/INN)), D01581 (Flufenamic acid (JAN/USAN/INN)), D01582 (Acemetacin (JP16/INN)), D01709 (Loxoprofen sodium hydrate (JP16)), D01765 (Proglumetacin maleate (JAN)), D01767 (Tenoxicam (JAN/USAN/INN)), D01788 (Amfenac sodium hydrate (JAN)), D01811 (Salicylamide (JAN/USP/INN)), D01866 (Lornoxicam (JAN/USAN/INN)), D01974 (Tilmacoxib (JAN/USAN/INN)), D02110 (Indometacin sodium (JAN)), D02290 (Flurbiprofen sodium (USP)), D02341 (Meclofenamic acid (USAN/INN)), D02350 (Fenoprofen (USAN/INN)), D02355 (Tolmetin (USAN/INN)), D02709 (Valdecoxib (USAN/INN)), D03254 (Flufenamate aluminum (JAN)), D03410 (Carprofen (USAN/INN)), D03652 (Darbufelone mesylate (USAN)), D03689 (Deracoxib (USAN)), D03710 (Etoricoxib (USAN/INN)), D03712 (Firocoxib (USAN/INN)), D03714 (Lumiracoxib (USAN/INN)), D03715 (Dexibuprofen (USAN/INN)), D03716 (Parecoxib (USAN/INN)), D03717 (Parecoxib sodium (USAN)), D03718 (Dexibuprofen lysine (USAN)), D04490 (Ibuprofen aluminum (USAN)), D05181 (Aspirin aluminum (JP16)), D05511 (Piroxicam betadex (USAN)), D05512 (Piroxicam cinnamate (USAN)), D05513 (Piroxicam olamine (USAN)), D06606 (Ibuprofen lysine (USAN)), D07269 (Dexketoprofen (INN)), D07421 (Aloxiprin (INN)), D07443 (Amfenac (INN)), D07516 (Benzydamine (INN)), D07517 (Benzydamine salicylate), D07579 (Aspirin calcium salt), D07580 (Aspirin DL-lysine (JAN)), D07581 (Aspirin magnesium salt), D07582 (Aspirin sodium), D07816 (Diclofenac (INN)), D07817 (Diclofenac diethylamine), D07818 (Diclofenac hydroxyethylpyrrolidine), D07819 (Diclofenac calcium), D08058 (Ibuprofen arginine salt), D08059 (Ibuprofen sodium), D08102 (Ketoprofen lysine), D08103 (Ketoprofen sodium), D08104 (Ketorolac (INN)), D08149 (Loxoprofen (INN)), D08363 (Phenylbutazone calcium), D08364 (Phenylbutazone sodium), D08374 (Piketoprofen (INN)), D08375 (Piketoprofen hydrochloride), D08427 (Proglumetacin (INN)), D09760 (Ibuprofen sodium (USAN))
rect (794,168) (840,185)	/dbget-bin/www_bget?hsa:100137049+hsa:123745+hsa:26279+hsa:30814+hsa:391013+hsa:50487+hsa:5319+hsa:5320+hsa:5321+hsa:5322+hsa:64600+hsa:81579+hsa:8398+hsa:8399+hsa:84647+hsa:8681+H00057+D02548+D03650+D03938+D06283+D08179	100137049 (PLA2G4B), 123745 (PLA2G4E), 26279 (PLA2G2D), 30814 (PLA2G2E), 391013 (PLA2G2C), 50487 (PLA2G3), 5319 (PLA2G1B), 5320 (PLA2G2A), 5321 (PLA2G4A), 5322 (PLA2G5), 64600 (PLA2G2F), 81579 (PLA2G12A), 8398 (PLA2G6), 8399 (PLA2G10), 84647 (PLA2G12B), 8681 (JMJD7-PLA2G4B), H00057 (Parkinson's disease (PD)), D02548 (Mepacrine dihydrochloride), D03650 (Darapladib (USAN)), D03938 (Ecopladib (USAN/INN)), D06283 (Varespladib sodium (USAN)), D08179 (Mepacrine (INN))
rect (605,357) (651,374)	/dbget-bin/www_bget?hsa:3315	3315 (HSPB1)
rect (496,357) (542,374)	/dbget-bin/www_bget?hsa:7867+hsa:9261	7867 (MAPKAPK3), 9261 (MAPKAPK2)
rect (497,222) (543,239)	/dbget-bin/www_bget?hsa:11261+hsa:5530+hsa:5532+hsa:5533+hsa:5534+hsa:5535+hsa:63928	11261 (CHP), 5530 (PPP3CA), 5532 (PPP3CB), 5533 (PPP3CC), 5534 (PPP3R1), 5535 (PPP3R2), 63928 (CHP2)
rect (350,489) (396,506)	/dbget-bin/www_bget?hsa:10000+hsa:207+hsa:208+H00027+H00420	10000 (AKT3), 207 (AKT1), 208 (AKT2), H00027 (Ovarian cancer), H00420 (Familial partial lipodystrophy (FPL), including the following four diseases:)
rect (247,410) (293,427)	/dbget-bin/www_bget?hsa:23533+hsa:5290+hsa:5291+hsa:5293+hsa:5294+hsa:5295+hsa:5296+hsa:8503+H00027	23533 (PIK3R5), 5290 (PIK3CA), 5291 (PIK3CB), 5293 (PIK3CD), 5294 (PIK3CG), 5295 (PIK3R1), 5296 (PIK3R2), 8503 (PIK3R3), H00027 (Ovarian cancer)
rect (580,222) (626,239)	/dbget-bin/www_bget?hsa:10725+hsa:4772+hsa:4773+hsa:4775+hsa:4776	10725 (NFAT5), 4772 (NFATC1), 4773 (NFATC2), 4775 (NFATC3), 4776 (NFATC4)
rect (433,147) (479,164)	/dbget-bin/www_bget?hsa:5578+hsa:5579+hsa:5582+H00063+D01066+D02970+D08401	5578 (PRKCA), 5579 (PRKCB), 5582 (PRKCG), H00063 (Spinocerebellar ataxia (SCA)), D01066 (Polymixin B sulfate (JP16)), D02970 (Aprinocarsen sodium (USAN)), D08401 (Polymyxin B (INN))
rect (495,290) (541,307)	/dbget-bin/www_bget?hsa:5747	5747 (PTK2)
rect (375,357) (421,374)	/dbget-bin/www_bget?hsa:1432+hsa:5600+hsa:5603+hsa:6300+D03736	1432 (MAPK14), 5600 (MAPK11), 5603 (MAPK13), 6300 (MAPK12), D03736 (Doramapimod (USAN/INN))
rect (495,312) (541,329)	/dbget-bin/www_bget?hsa:5829	5829 (PXN)
rect (247,174) (293,191)	/dbget-bin/www_bget?hsa:9047	9047 (SH2D2A)
rect (176,377) (222,394)	/dbget-bin/www_bget?hsa:6714+D03252+D03658+D06414+D09728	6714 (SRC), D03252 (Bosutinib (USAN)), D03658 (Dasatinib (INN)), D06414 (Dasatinib hydrate (JAN)), D09728 (Bosutinib hydrate (JAN))
rect (247,255) (293,272)	/dbget-bin/www_bget?hsa:25759	25759 (SHC2)
rect (49,301) (95,318)	/dbget-bin/www_bget?hsa:7422+H00018+D06409	7422 (VEGFA), H00018 (Gastric cancer), D06409 (Bevacizumab (genetical recombination) (JAN))
rect (756,126) (802,143)	/dbget-bin/www_bget?hsa:5594+hsa:5595	5594 (MAPK1), 5595 (MAPK3)
rect (680,126) (726,143)	/dbget-bin/www_bget?hsa:5604+hsa:5605	5604 (MAP2K1), 5605 (MAP2K2)
rect (630,100) (676,117)	/dbget-bin/www_bget?hsa:5894	5894 (RAF1)
rect (553,89) (599,106)	/dbget-bin/www_bget?hsa:3265+hsa:3845+hsa:4893+H00003+H00010+H00014+H00016+H00018+H00019+H00020+H00022+H00025+H00026+H00027+H00030+H00032+H00033+H00038+H00040+H00041+H00046+H00047+H00048+H00108	3265 (HRAS), 3845 (KRAS), 4893 (NRAS), H00003 (Acute myeloid leukemia (AML)), H00010 (Multiple myeloma), H00014 (Non-small cell lung cancer), H00016 (Oral cancer), H00018 (Gastric cancer), H00019 (Pancreatic cancer), H00020 (Colorectal cancer), H00022 (Bladder cancer), H00025 (Penile cancer), H00026 (Endometrial Cancer), H00027 (Ovarian cancer), H00030 (Cervical cancer), H00032 (Thyroid cancer), H00033 (Adrenal carcinoma), H00038 (Malignant melanoma), H00040 (Squamous cell carcinoma), H00041 (Kaposi's sarcoma), H00046 (Cholangiocarcinoma), H00047 (Gallbladder cancer), H00048 (Hepatocellular carcinoma), H00108 (Autoimmune lymphoproliferative syndromes (ALPS), including the following five diseases:)
rect (468,463) (514,480)	/dbget-bin/www_bget?hsa:4846	4846 (NOS3)
rect (468,502) (514,519)	/dbget-bin/www_bget?hsa:842	842 (CASP9)
rect (468,541) (514,558)	/dbget-bin/www_bget?hsa:572	572 (BAD)
rect (531,411) (577,428)	/dbget-bin/www_bget?hsa:5879+hsa:5880+hsa:5881+H00099	5879 (RAC1), 5880 (RAC2), 5881 (RAC3), H00099 (Leukocyte adhesion deficiency (LAD), including the following four diseases:)
rect (294,111) (404,145)	/kegg-bin/show_pathway?hsadd04020	hsadd04020: Calcium signaling pathway
rect (294,527) (395,552)	/kegg-bin/show_pathway?hsadd04210	hsadd04210: Apoptosis
rect (558,266) (668,291)	/kegg-bin/show_pathway?hsadd04510	hsadd04510: Focal adhesion
rect (558,139) (668,173)	/kegg-bin/show_pathway?hsadd04010	hsadd04010: MAPK signaling pathway
rect (40,45) (262,70)	/dbget-bin/www_bget?hsa04370	hsadd04370: VEGF signaling pathway
rect (853,170) (963,204)	/kegg-bin/show_pathway?hsadd00590	hsadd00590: Arachidonic acid metabolism