circ (551,657) 4	/dbget-bin/www_bget?C05606	C05606 (Melanin)
circ (357,656) 4	/dbget-bin/www_bget?C00082	C00082 (L-Tyrosine)
circ (443,429) 4	/dbget-bin/www_bget?C00076	C00076 (Calcium cation)
circ (342,429) 4	/dbget-bin/www_bget?C01245	C01245 (D-myo-Inositol 1,4,5-trisphosphate)
circ (342,476) 4	/dbget-bin/www_bget?C00165	C00165 (Diacylglycerol)
circ (222,189) 4	/dbget-bin/www_bget?C00575	C00575 (3',5'-Cyclic AMP)
rect (314,266) (360,283)	/dbget-bin/www_bget?hsa:1855+hsa:1856+hsa:1857	1855 (DVL1), 1856 (DVL2), 1857 (DVL3)
rect (487,582) (533,599)	/dbget-bin/www_bget?hsa:1638	1638 (DCT)
rect (429,582) (475,599)	/dbget-bin/www_bget?hsa:7306+H00168	7306 (TYRP1), H00168 (Oculocutaneous albinism (OCA))
rect (372,582) (418,599)	/dbget-bin/www_bget?hsa:7299+H00168	7299 (TYR), H00168 (Oculocutaneous albinism (OCA))
rect (509,319) (555,336)	/dbget-bin/www_bget?hsa:4286+H00038+H00169	4286 (MITF), H00038 (Malignant melanoma), H00169 (Ocular albinism)
rect (779,416) (825,433)	/dbget-bin/www_bget?hsa:1638	1638 (DCT)
rect (779,394) (825,411)	/dbget-bin/www_bget?hsa:7306+H00168	7306 (TYRP1), H00168 (Oculocutaneous albinism (OCA))
rect (779,371) (825,388)	/dbget-bin/www_bget?hsa:7299+H00168	7299 (TYR), H00168 (Oculocutaneous albinism (OCA))
rect (466,468) (512,485)	/dbget-bin/www_bget?hsa:5566+hsa:5567+hsa:5568+hsa:5613	5566 (PRKACA), 5567 (PRKACB), 5568 (PRKACG), 5613 (PRKX)
rect (548,421) (594,438)	/dbget-bin/www_bget?hsa:815+hsa:816+hsa:817+hsa:818	815 (CAMK2A), 816 (CAMK2B), 817 (CAMK2D), 818 (CAMK2G)
rect (475,421) (521,438)	/dbget-bin/www_bget?hsa:163688+hsa:51806+hsa:801+hsa:805+hsa:808+hsa:810	163688 (CALML6), 51806 (CALML5), 801 (CALM1), 805 (CALM2), 808 (CALM3), 810 (CALML3)
rect (190,443) (236,460)	/dbget-bin/www_bget?hsa:2770+hsa:2771+hsa:2773+hsa:2775+H00033	2770 (GNAI1), 2771 (GNAI2), 2773 (GNAI3), 2775 (GNAO1), H00033 (Adrenal carcinoma)
rect (116,443) (162,460)	/dbget-bin/www_bget?hsa:1910+H00054+D01227+D07538	1910 (EDNRB), H00054 (Nasopharyngeal cancer), D01227 (Bosentan hydrate (JAN)), D07538 (Bosentan (INN))
rect (116,354) (162,371)	/dbget-bin/www_bget?hsa:3815+H00003+H00170+D01441+D03218+D03658+D05029+D05380+D05819+D06005+D06272+D06285+D06402+D06413+D06414+D06678+D08066+D08524+D08552+D08947+D08953	3815 (KIT), H00003 (Acute myeloid leukemia (AML)), H00170 (Piebaldism), D01441 (Imatinib mesilate (JAN)), D03218 (Axitinib (JAN/USAN)), D03658 (Dasatinib (INN)), D05029 (Midostaurin (USAN/INN)), D05380 (Pazopanib hydrochloride (JAN/USAN)), D05819 (Semaxanib (USAN/INN)), D06005 (Tandutinib (USAN/INN)), D06272 (Sorafenib tosilate (JAN)), D06285 (Vatalanib (USAN/INN)), D06402 (Sunitinib malate (JAN/USAN)), D06413 (Nilotinib hydrochloride hydrate (JAN)), D06414 (Dasatinib hydrate (JAN)), D06678 (Motesanib), D08066 (Imatinib (INN)), D08524 (Sorafenib (USAN/INN)), D08552 (Sunitinib (INN)), D08947 (Motesanib diphosphate (USAN)), D08953 (Nilotinib (INN/USAN))
rect (779,226) (825,243)	/dbget-bin/www_bget?hsa:4286+H00038+H00169	4286 (MITF), H00038 (Malignant melanoma), H00169 (Ocular albinism)
rect (43,354) (89,371)	/dbget-bin/www_bget?hsa:4254	4254 (KITLG)
rect (116,266) (162,283)	/dbget-bin/www_bget?hsa:11211+hsa:2535+hsa:7855+hsa:7976+hsa:8321+hsa:8322+hsa:8323+hsa:8324+hsa:8325+hsa:8326	11211 (FZD10), 2535 (FZD2), 7855 (FZD5), 7976 (FZD3), 8321 (FZD1), 8322 (FZD4), 8323 (FZD6), 8324 (FZD7), 8325 (FZD8), 8326 (FZD9)
rect (262,443) (308,460)	/dbget-bin/www_bget?hsa:23236+hsa:5330+hsa:5331+hsa:5332	23236 (PLCB1), 5330 (PLCB2), 5331 (PLCB3), 5332 (PLCB4)
rect (43,158) (89,175)	/dbget-bin/www_bget?hsa:434	434 (ASIP)
rect (658,198) (704,215)	/dbget-bin/www_bget?hsa:1387+hsa:2033	1387 (CREBBP), 2033 (EP300)
rect (267,180) (313,197)	/dbget-bin/www_bget?hsa:5566+hsa:5567+hsa:5568+hsa:5613	5566 (PRKACA), 5567 (PRKACB), 5568 (PRKACG), 5613 (PRKX)
rect (658,265) (704,282)	/dbget-bin/www_bget?hsa:51176+hsa:6932+hsa:6934+hsa:83439+H00409	51176 (LEF1), 6932 (TCF7), 6934 (TCF7L2), 83439 (TCF7L1), H00409 (Type II diabetes mellitus)
rect (198,124) (244,141)	/dbget-bin/www_bget?hsa:2778	2778 (GNAS)
rect (302,537) (348,554)	/dbget-bin/www_bget?hsa:5579+D01066+D08401	5579 (PRKCB), D01066 (Polymixin B sulfate (JP16)), D08401 (Polymyxin B (INN))
rect (658,181) (704,198)	/dbget-bin/www_bget?hsa:10488+hsa:1385+hsa:148327+hsa:64764+hsa:84699+hsa:90993	10488 (CREB3), 1385 (CREB1), 148327 (CREB3L4), 64764 (CREB3L2), 84699 (CREB3L3), 90993 (CREB3L1)
rect (116,179) (162,196)	/dbget-bin/www_bget?hsa:107+hsa:108+hsa:109+hsa:111+hsa:112+hsa:113+hsa:114+hsa:115+hsa:196883	107 (ADCY1), 108 (ADCY2), 109 (ADCY3), 111 (ADCY5), 112 (ADCY6), 113 (ADCY7), 114 (ADCY8), 115 (ADCY9), 196883 (ADCY4)
rect (384,468) (430,485)	/dbget-bin/www_bget?hsa:5578+hsa:5579+hsa:5582+H00063+D01066+D02970+D08401	5578 (PRKCA), 5579 (PRKCB), 5582 (PRKCG), H00063 (Spinocerebellar ataxia (SCA)), D01066 (Polymixin B sulfate (JP16)), D02970 (Aprinocarsen sodium (USAN)), D08401 (Polymyxin B (INN))
rect (413,266) (459,283)	/dbget-bin/www_bget?hsa:2932	2932 (GSK3B)
rect (512,266) (558,283)	/dbget-bin/www_bget?hsa:1499+H00018+H00020+H00026+H00032+H00048	1499 (CTNNB1), H00018 (Gastric cancer), H00020 (Colorectal cancer), H00026 (Endometrial Cancer), H00032 (Thyroid cancer), H00048 (Hepatocellular carcinoma)
rect (43,124) (89,141)	/dbget-bin/www_bget?hsa:5443	5443 (POMC)
rect (215,266) (261,283)	/dbget-bin/www_bget?hsa:2775+hsa:2776	2775 (GNAO1), 2776 (GNAQ)
rect (116,124) (162,141)	/dbget-bin/www_bget?hsa:4157+D00146+D00284+D02105+D03593+D06544	4157 (MC1R), D00146 (Corticotropin (USP/INN)), D00284 (Cosyntropin (USAN)), D02105 (Tetracosactide acetate (JAN)), D03593 (Corticotropin zinc hydroxide (USP)), D06544 (Corticotropin, repository (USP))
rect (43,266) (89,283)	/dbget-bin/www_bget?hsa:51384+hsa:54361+hsa:7471+hsa:7472+hsa:7473+hsa:7474+hsa:7475+hsa:7476+hsa:7477+hsa:7478+hsa:7479+hsa:7480+hsa:7481+hsa:7482+hsa:7483+hsa:7484+hsa:80326+hsa:81029+hsa:89780	51384 (WNT16), 54361 (WNT4), 7471 (WNT1), 7472 (WNT2), 7473 (WNT3), 7474 (WNT5A), 7475 (WNT6), 7476 (WNT7A), 7477 (WNT7B), 7478 (WNT8A), 7479 (WNT8B), 7480 (WNT10B), 7481 (WNT11), 7482 (WNT2B), 7483 (WNT9A), 7484 (WNT9B), 80326 (WNT10A), 81029 (WNT5B), 89780 (WNT3A)
rect (433,354) (479,371)	/dbget-bin/www_bget?hsa:5594+hsa:5595	5594 (MAPK1), 5595 (MAPK3)
rect (353,354) (399,371)	/dbget-bin/www_bget?hsa:5604+hsa:5605	5604 (MAP2K1), 5605 (MAP2K2)
rect (274,354) (320,371)	/dbget-bin/www_bget?hsa:5894	5894 (RAF1)
rect (194,354) (240,371)	/dbget-bin/www_bget?hsa:3265+hsa:3845+hsa:4893+H00003+H00010+H00014+H00016+H00018+H00019+H00020+H00022+H00025+H00026+H00027+H00030+H00032+H00033+H00038+H00040+H00041+H00046+H00047+H00048+H00108	3265 (HRAS), 3845 (KRAS), 4893 (NRAS), H00003 (Acute myeloid leukemia (AML)), H00010 (Multiple myeloma), H00014 (Non-small cell lung cancer), H00016 (Oral cancer), H00018 (Gastric cancer), H00019 (Pancreatic cancer), H00020 (Colorectal cancer), H00022 (Bladder cancer), H00025 (Penile cancer), H00026 (Endometrial Cancer), H00027 (Ovarian cancer), H00030 (Cervical cancer), H00032 (Thyroid cancer), H00033 (Adrenal carcinoma), H00038 (Malignant melanoma), H00040 (Squamous cell carcinoma), H00041 (Kaposi's sarcoma), H00046 (Cholangiocarcinoma), H00047 (Gallbladder cancer), H00048 (Hepatocellular carcinoma), H00108 (Autoimmune lymphoproliferative syndromes (ALPS), including the following five diseases:)
rect (43,443) (89,460)	/dbget-bin/www_bget?hsa:1906	1906 (EDN1)
rect (40,45) (181,70)	/dbget-bin/www_bget?hsa04916	hsadd04916: Melanogenesis
rect (266,222) (375,256)	/kegg-bin/show_pathway?hsadd04310	hsadd04310: Wnt signaling pathway
rect (398,640) (507,674)	/kegg-bin/show_pathway?hsadd00350	hsadd00350: Tyrosine metabolism
rect (640,353) (732,378)	/kegg-bin/show_pathway?hsadd05218	hsadd05218: Melanoma
rect (264,312) (374,346)	/kegg-bin/show_pathway?hsadd04010	hsadd04010: MAPK signaling pathway