circ (425,540) 4	/dbget-bin/www_bget?C01245	C01245 (D-myo-Inositol 1,4,5-trisphosphate)
circ (408,595) 4	/dbget-bin/www_bget?C00076	C00076 (Calcium cation)
circ (744,514) 4	/dbget-bin/www_bget?C00076	C00076 (Calcium cation)
circ (561,702) 4	/dbget-bin/www_bget?C00533	C00533 (Nitric oxide)
circ (638,703) 4	/dbget-bin/www_bget?C16845	C16845 (Peroxynitrite)
circ (681,513) 4	/dbget-bin/www_bget?C00076	C00076 (Calcium cation)
circ (238,751) 4	/dbget-bin/www_bget?C00027	C00027 (Hydrogen peroxide)
circ (201,695) 4	/dbget-bin/www_bget?C00070	C00070 (Copper)
circ (201,725) 4	/dbget-bin/www_bget?C14818	C14818 (Fe2+)
rect (356,271) (402,288)	/dbget-bin/www_bget?hsa:55851	55851 (PSENEN)
rect (402,271) (448,288)	/dbget-bin/www_bget?hsa:5663+hsa:5664+H00056	5663 (PSEN1), 5664 (PSEN2), H00056 (Alzheimer's disease (AD))
rect (356,288) (402,305)	/dbget-bin/www_bget?hsa:23385	23385 (NCSTN)
rect (402,288) (448,305)	/dbget-bin/www_bget?hsa:51107	51107 (APH1A)
rect (376,221) (422,238)	/dbget-bin/www_bget?hsa:23621+hsa:25825	23621 (BACE1), 25825 (BACE2)
rect (374,118) (420,135)	/dbget-bin/www_bget?hsa:102+hsa:6868	102 (ADAM10), 6868 (ADAM17)
rect (172,786) (218,803)	/dbget-bin/www_bget?hsa:7124+H00079+H00080+H00083+H00084+D02597+D02598+D03441+D04358+D04687+D09813	7124 (TNF), H00079 (Asthma), H00080 (Systemic lupus erythematosus), H00083 (Allograft rejection), H00084 (Graft-versus-host disease), D02597 (Adalimumab (genetical recombination) (JAN)), D02598 (Infliximab (genetical recombination) (JAN)), D03441 (Certolizumab pegol (genetical recombination) (JAN)), D04358 (Golimumab (genetical recombination) (JAN)), D04687 (Lenalidomide (USAN/INN)), D09813 (Lenalidomide hydrate (JAN))
rect (253,166) (299,183)	/dbget-bin/www_bget?hsa:351+H00056	351 (APP), H00056 (Alzheimer's disease (AD))
rect (787,420) (833,437)	/dbget-bin/www_bget?hsa:842	842 (CASP9)
rect (862,420) (908,437)	/dbget-bin/www_bget?hsa:836	836 (CASP3)
rect (689,401) (735,418)	/dbget-bin/www_bget?hsa:54205	54205 (CYCS)
rect (689,439) (735,456)	/dbget-bin/www_bget?hsa:317	317 (APAF1)
rect (546,201) (592,218)	/dbget-bin/www_bget?hsa:126328+hsa:374291+hsa:4694+hsa:4695+hsa:4696+hsa:4697+hsa:4698+hsa:4700+hsa:4701+hsa:4702+hsa:4704+hsa:4705+hsa:4706+hsa:4707+hsa:4708+hsa:4709+hsa:4710+hsa:4711+hsa:4712+hsa:4713+hsa:4714+hsa:4715+hsa:4716+hsa:4717+hsa:4718+hsa:4719+hsa:4720+hsa:4722+hsa:4723+hsa:4724+hsa:4725+hsa:4726+hsa:4728+hsa:4729+hsa:4731+hsa:51079+hsa:54539+hsa:55967+hsa:56901	126328 (NDUFA11), 374291 (NDUFS7), 4694 (NDUFA1), 4695 (NDUFA2), 4696 (NDUFA3), 4697 (NDUFA4), 4698 (NDUFA5), 4700 (NDUFA6), 4701 (NDUFA7), 4702 (NDUFA8), 4704 (NDUFA9), 4705 (NDUFA10), 4706 (NDUFAB1), 4707 (NDUFB1), 4708 (NDUFB2), 4709 (NDUFB3), 4710 (NDUFB4), 4711 (NDUFB5), 4712 (NDUFB6), 4713 (NDUFB7), 4714 (NDUFB8), 4715 (NDUFB9), 4716 (NDUFB10), 4717 (NDUFC1), 4718 (NDUFC2), 4719 (NDUFS1), 4720 (NDUFS2), 4722 (NDUFS3), 4723 (NDUFV1), 4724 (NDUFS4), 4725 (NDUFS5), 4726 (NDUFS6), 4728 (NDUFS8), 4729 (NDUFV2), 4731 (NDUFV3), 51079 (NDUFA13), 54539 (NDUFB11), 55967 (NDUFA12), 56901 (NDUFA4L2)
rect (546,230) (592,247)	/dbget-bin/www_bget?hsa:6389+hsa:6390+hsa:6391+hsa:6392+H00034	6389 (SDHA), 6390 (SDHB), 6391 (SDHC), 6392 (SDHD), H00034 (Carcinoid)
rect (546,258) (592,275)	/dbget-bin/www_bget?hsa:10975+hsa:1537+hsa:27089+hsa:29796+hsa:440567+hsa:4519+hsa:7381+hsa:7384+hsa:7385+hsa:7386+hsa:7388+H00068	10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL), 4519 (CYTB), 7381 (UQCRB), 7384 (UQCRC1), 7385 (UQCRC2), 7386 (UQCRFS1), 7388 (UQCRH), H00068 (Leber optic atrophy)
rect (546,316) (592,333)	/dbget-bin/www_bget?hsa:10476+hsa:4508+hsa:4509+hsa:498+hsa:506+hsa:509+hsa:513+hsa:514+hsa:515+hsa:516+hsa:517+hsa:518+hsa:522+hsa:539+H00068	10476 (ATP5H), 4508 (ATP6), 4509 (ATP8), 498 (ATP5A1), 506 (ATP5B), 509 (ATP5C1), 513 (ATP5D), 514 (ATP5E), 515 (ATP5F1), 516 (ATP5G1), 517 (ATP5G2), 518 (ATP5G3), 522 (ATP5J), 539 (ATP5O), H00068 (Leber optic atrophy)
rect (546,288) (592,305)	/dbget-bin/www_bget?hsa:125965+hsa:1327+hsa:1329+hsa:1337+hsa:1339+hsa:1340+hsa:1345+hsa:1346+hsa:1347+hsa:1349+hsa:1350+hsa:1351+hsa:170712+hsa:341947+hsa:4512+hsa:4513+hsa:4514+hsa:84701+hsa:9167+hsa:9377+H00068	125965 (COX6B2), 1327 (COX4I1), 1329 (COX5B), 1337 (COX6A1), 1339 (COX6A2), 1340 (COX6B1), 1345 (COX6C), 1346 (COX7A1), 1347 (COX7A2), 1349 (COX7B), 1350 (COX7C), 1351 (COX8A), 170712 (COX7B2), 341947 (COX8C), 4512 (COX1), 4513 (COX2), 4514 (COX3), 84701 (COX4I2), 9167 (COX7A2L), 9377 (COX5A), H00068 (Leber optic atrophy)
rect (564,576) (610,593)	/dbget-bin/www_bget?hsa:6263+D00740+D00808	6263 (RYR3), D00740 (Procaine hydrochloride (JP16/USP)), D00808 (Suramin hexasodium (USAN))
rect (564,606) (610,623)	/dbget-bin/www_bget?hsa:3708+hsa:3709+hsa:3710+H00063+H00408	3708 (ITPR1), 3709 (ITPR2), 3710 (ITPR3), H00063 (Spinocerebellar ataxia (SCA)), H00408 (Type I diabetes mellitus)
rect (720,547) (766,564)	/dbget-bin/www_bget?hsa:487+hsa:488+hsa:489	487 (ATP2A1), 488 (ATP2A2), 489 (ATP2A3)
rect (656,548) (702,565)	/dbget-bin/www_bget?hsa:5663+hsa:5664+H00056	5663 (PSEN1), 5664 (PSEN2), H00056 (Alzheimer's disease (AD))
rect (329,489) (375,506)	/dbget-bin/www_bget?hsa:2776	2776 (GNAQ)
rect (401,490) (447,507)	/dbget-bin/www_bget?hsa:23236+hsa:5330+hsa:5331+hsa:5332	23236 (PLCB1), 5330 (PLCB2), 5331 (PLCB3), 5332 (PLCB4)
rect (255,588) (301,605)	/dbget-bin/www_bget?hsa:2902+hsa:2903+hsa:2904+hsa:2905+hsa:2906+D00711+D00848+D01445+D02102+D02410+D02973+D03100+D03679+D03742+D03746+D03878+D04226+D04308+D04728+D04905+D05145+D05447+D05453+D05714+D06204+D07283+D08098+D08121+D08122+D08174+D08195	2902 (GRIN1), 2903 (GRIN2A), 2904 (GRIN2B), 2905 (GRIN2C), 2906 (GRIN2D), D00711 (Ketamine hydrochloride (JP16/USP)), D00848 (Dextromethorphan hydrobromide hydrate (JP16)), D01445 (Ifenprodil tartrate (JP16)), D02102 (Methadone hydrochloride (USP)), D02410 (Selfotel (USAN/INN)), D02973 (Aptiganel hydrochloride (USAN)), D03100 (Besonprodil (USAN)), D03679 (Delucemine hydrochloride (USAN)), D03742 (Dextromethorphan (USP)), D03746 (Dextrorphan hydrochloride (USAN)), D03878 (Dizocilpine maleate (USAN)), D04226 (Flupirtine maleate (USAN)), D04308 (Gavestinel (USAN/INN)), D04728 (Licostinel (USAN/INN)), D04905 (Memantine hydrochloride (JAN/USAN)), D05145 (Neramexane mesylate (USAN)), D05447 (Perzinfotel (USAN/INN)), D05453 (Phencyclidine hydrochloride (USAN)), D05714 (Remacemide hydrochloride (USAN)), D06204 (Traxoprodil mesylate (USAN)), D07283 (Esketamine (INN)), D08098 (Ketamine (INN)), D08121 (Levomethadone (INN)), D08122 (Levomethadone hydrochloride), D08174 (Memantine (INN)), D08195 (Methadone (BAN))
rect (255,623) (301,640)	/dbget-bin/www_bget?hsa:775+hsa:776+hsa:778+hsa:779+H00215+D00319+D00349+D00437+D00438+D00537+D00615+D00616+D00617+D00618+D00619+D00629+D00631+D01104+D01145+D01173+D01553+D01562+D01604+D01908+D01969+D02045+D02356+D02537+D02914+D03655+D03830+D03914+D04657+D07450+D07494+D07509+D07520+D07845+D07886+D08009+D08155+D08270	775 (CACNA1C), 776 (CACNA1D), 778 (CACNA1F), 779 (CACNA1S), H00215 (Periodic paralysis), D00319 (Felodipine (JAN/USP/INN)), D00349 (Isradipine (USP/INN)), D00437 (Nifedipine (JP16/USP/INN)), D00438 (Nimodipine (USAN/INN)), D00537 (Topiramate (JAN/USAN/INN)), D00615 (Amlodipine besilate (JP16)), D00616 (Diltiazem hydrochloride (JP16/USP)), D00617 (Nicardipine hydrochloride (JP16/USAN)), D00618 (Nisoldipine (JAN/USAN/INN)), D00619 (Verapamil hydrochloride (JP16/USP)), D00629 (Nitrendipine (JP16/USAN/INN)), D00631 (Bepridil hydrochloride hydrate (JAN)), D01104 (Barnidipine hydrochloride (JAN)), D01145 (Azelnidipine (JAN/INN)), D01173 (Cilnidipine (JAN/INN)), D01553 (Manidipine hydrochloride (JP16)), D01562 (Aranidipine (JAN/INN)), D01604 (Efonidipine hydrochloride ethanolate (JAN)), D01908 (Nilvadipine (JP16/USAN/INN)), D01969 (Gallopamil hydrochloride (JAN)), D02045 (Benidipine hydrochloride (JP16)), D02356 (Verapamil (USAN/INN)), D02537 (Dronedarone (INN)), D02914 (Amlodipine maleate (USAN)), D03655 (Darodipine (USAN/INN)), D03830 (Diltiazem malate (USAN)), D03914 (Dronedarone hydrochloride (USAN)), D04657 (Lacidipine (USAN/INN)), D07450 (Amlodipine (INN)), D07494 (Barnidipine (INN)), D07509 (Benidipine (INN)), D07520 (Bepridil (INN)), D07845 (Diltiazem (INN)), D07886 (Efonidipine (INN)), D08009 (Gallopamil (INN)), D08155 (Manidipine (INN)), D08270 (Nicardipine (INN))
rect (614,325) (660,342)	/dbget-bin/www_bget?hsa:3028	3028 (HSD17B10)
rect (386,692) (432,709)	/dbget-bin/www_bget?hsa:823+hsa:824	823 (CAPN1), 824 (CAPN2)
rect (386,743) (432,760)	/dbget-bin/www_bget?hsa:8851	8851 (CDK5R1)
rect (475,743) (521,760)	/dbget-bin/www_bget?hsa:8851	8851 (CDK5R1)
rect (475,783) (521,800)	/dbget-bin/www_bget?hsa:1020	1020 (CDK5)
rect (588,763) (634,780)	/dbget-bin/www_bget?hsa:4137+H00058+H00077+H00078	4137 (MAPT), H00058 (Amyotrophic lateral sclerosis (ALS)), H00077 (Progressive supranuclear palsy (PSP)), H00078 (Pick's disease)
rect (254,423) (300,440)	/dbget-bin/www_bget?hsa:355+hsa:7132+H00005+H00007+H00009+H00017+D00742	355 (FAS), 7132 (TNFRSF1A), H00005 (Chronic lymphocytic leukemia (CLL)), H00007 (Hodgkin lymphoma), H00009 (Adult T-cell leukemia), H00017 (Esophageal cancer), D00742 (Etanercept (genetical recombination) (JAN))
rect (327,424) (373,441)	/dbget-bin/www_bget?hsa:8772	8772 (FADD)
rect (400,424) (446,441)	/dbget-bin/www_bget?hsa:841+H00108	841 (CASP8), H00108 (Autoimmune lymphoproliferative syndromes (ALPS), including the following five diseases:)
rect (471,424) (517,441)	/dbget-bin/www_bget?hsa:637	637 (BID)
rect (566,493) (612,510)	/dbget-bin/www_bget?hsa:5594+hsa:5595	5594 (MAPK1), 5595 (MAPK3)
rect (445,692) (491,709)	/dbget-bin/www_bget?hsa:4842	4842 (NOS1)
rect (636,631) (682,648)	/dbget-bin/www_bget?hsa:9451	9451 (EIF2AK3)
rect (691,631) (737,648)	/dbget-bin/www_bget?hsa:2081	2081 (ERN1)
rect (745,631) (791,648)	/dbget-bin/www_bget?hsa:22926	22926 (ATF6)
rect (188,392) (234,409)	/dbget-bin/www_bget?hsa:348+H00056+H00156	348 (APOE), H00056 (Alzheimer's disease (AD)), H00156 (Hyperlipoproteinemia, type III)
rect (544,446) (590,463)	/dbget-bin/www_bget?hsa:163688+hsa:51806+hsa:801+hsa:805+hsa:808+hsa:810	163688 (CALML6), 51806 (CALML5), 801 (CALM1), 805 (CALM2), 808 (CALM3), 810 (CALML3)
rect (614,446) (660,463)	/dbget-bin/www_bget?hsa:11261+hsa:5530+hsa:5532+hsa:5533+hsa:5534+hsa:5535+hsa:63928	11261 (CHP), 5530 (PPP3CA), 5532 (PPP3CB), 5533 (PPP3CC), 5534 (PPP3R1), 5535 (PPP3R2), 63928 (CHP2)
rect (632,406) (678,423)	/dbget-bin/www_bget?hsa:572	572 (BAD)
rect (104,315) (150,332)	/dbget-bin/www_bget?hsa:3416	3416 (IDE)
rect (104,351) (150,368)	/dbget-bin/www_bget?hsa:4311+D01070+D03349+D03929	4311 (MME), D01070 (Candoxatril (JAN/USAN/INN)), D03349 (Candoxatrilat (USAN/INN)), D03929 (Ecadotril (USAN/INN))
rect (333,168) (379,185)	/dbget-bin/www_bget?hsa:322	322 (APBB1)
rect (254,383) (300,400)	/dbget-bin/www_bget?hsa:4035	4035 (LRP1)
rect (188,375) (234,392)	/dbget-bin/www_bget?hsa:4023+H00154+D03747	4023 (LPL), H00154 (Hyperlipoproteinemia, type I), D03747 (Ibrolipim (USAN/INN))
rect (333,192) (379,209)	/dbget-bin/www_bget?hsa:2597	2597 (GAPDH)
rect (333,144) (379,161)	/dbget-bin/www_bget?hsa:8883	8883 (NAE1)
rect (640,805) (686,822)	/dbget-bin/www_bget?hsa:836	836 (CASP3)
rect (640,828) (686,845)	/dbget-bin/www_bget?hsa:840	840 (CASP7)
rect (557,797) (603,814)	/dbget-bin/www_bget?hsa:2932	2932 (GSK3B)
rect (104,494) (150,511)	/dbget-bin/www_bget?hsa:6622+H00057+H00066	6622 (SNCA), H00057 (Parkinson's disease (PD)), H00066 (Lewy body dementia (LBD))
rect (172,822) (218,839)	/dbget-bin/www_bget?hsa:3553+D09315	3553 (IL1B), D09315 (Canakinumab (genetical recombination) (JAN))
rect (40,45) (224,70)	/dbget-bin/www_bget?hsa05010	hsadd05010: Alzheimer's disease
rect (512,120) (625,154)	/kegg-bin/show_pathway?hsadd00190	hsadd00190: Oxidative phosphorylation
rect (830,387) (943,412)	/kegg-bin/show_pathway?hsadd04210	hsadd04210: Apoptosis
rect (467,633) (580,667)	/kegg-bin/show_pathway?hsadd04020	hsadd04020: Calcium signaling pathway