circ (1146,549) 4	/dbget-bin/www_bget?C00027	C00027 (Hydrogen peroxide)
circ (457,139) 4	/dbget-bin/www_bget?C00434	C00434 (Double-stranded DNA)
circ (474,208) 4	/dbget-bin/www_bget?C02737	C02737 (Phosphatidylserine)
rect (1055,592) (1101,609)	/dbget-bin/www_bget?hsa:2209+hsa:2212+hsa:2213+hsa:2214+hsa:2215+hsa:9103+H00080+H00090	2209 (FCGR1A), 2212 (FCGR2A), 2213 (FCGR2B), 2214 (FCGR3A), 2215 (FCGR3B), 9103 (FCGR2C), H00080 (Systemic lupus erythematosus), H00090 (NK cell defects, including the following disease:)
rect (1056,693) (1102,710)	/dbget-bin/www_bget?hsa:2209+hsa:2212+hsa:2213+hsa:2214+hsa:2215+hsa:9103+H00080+H00090	2209 (FCGR1A), 2212 (FCGR2A), 2213 (FCGR2B), 2214 (FCGR3A), 2215 (FCGR3B), 9103 (FCGR2C), H00080 (Systemic lupus erythematosus), H00090 (NK cell defects, including the following disease:)
rect (1122,524) (1168,541)	/dbget-bin/www_bget?hsa:1991+H00100+D01918+D03788	1991 (ELANE), H00100 (Neutropenic disorders, including the following three diseases:), D01918 (Sivelestat sodium hydrate (JAN)), D03788 (Sivelestat (USAN/INN))
rect (1122,503) (1168,520)	/dbget-bin/www_bget?hsa:1511	1511 (CTSG)
rect (942,377) (988,394)	/dbget-bin/www_bget?hsa:727+H00103+D03940	727 (C5), H00103 (Late complement pathway defects, including the following seven diseases:), D03940 (Eculizumab (genetical recombination) (JAN))
rect (920,182) (966,199)	/dbget-bin/www_bget?hsa:720+hsa:721+H00080+H00102	720 (C4A), 721 (C4B), H00080 (Systemic lupus erythematosus), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (920,264) (966,281)	/dbget-bin/www_bget?hsa:718+H00102	718 (C3), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (920,203) (966,220)	/dbget-bin/www_bget?hsa:717+H00080+H00102	717 (C2), H00080 (Systemic lupus erythematosus), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (1004,153) (1050,170)	/dbget-bin/www_bget?hsa:716+H00102	716 (C1S), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (1050,144) (1096,161)	/dbget-bin/www_bget?hsa:712+hsa:713+hsa:714+H00102	712 (C1QA), 713 (C1QB), 714 (C1QC), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (1004,136) (1050,153)	/dbget-bin/www_bget?hsa:715+H00102	715 (C1R), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (1086,377) (1132,394)	/dbget-bin/www_bget?hsa:729+H00103	729 (C6), H00103 (Late complement pathway defects, including the following seven diseases:)
rect (1135,377) (1181,394)	/dbget-bin/www_bget?hsa:730+H00103	730 (C7), H00103 (Late complement pathway defects, including the following seven diseases:)
rect (1086,398) (1132,415)	/dbget-bin/www_bget?hsa:731+hsa:732+hsa:733+H00103	731 (C8A), 732 (C8B), 733 (C8G), H00103 (Late complement pathway defects, including the following seven diseases:)
rect (1227,346) (1273,363)	/dbget-bin/www_bget?hsa:727+hsa:729+hsa:730+hsa:731+hsa:732+hsa:733+H00103+D03940	727 (C5), 729 (C6), 730 (C7), 731 (C8A), 732 (C8B), 733 (C8G), H00103 (Late complement pathway defects, including the following seven diseases:), D03940 (Eculizumab (genetical recombination) (JAN))
rect (1135,398) (1181,415)	/dbget-bin/www_bget?hsa:735+H00103	735 (C9), H00103 (Late complement pathway defects, including the following seven diseases:)
rect (527,522) (573,539)	/dbget-bin/www_bget?hsa:7124+H00079+H00080+H00083+H00084+D02597+D02598+D03441+D04358+D04687+D09813	7124 (TNF), H00079 (Asthma), H00080 (Systemic lupus erythematosus), H00083 (Allograft rejection), H00084 (Graft-versus-host disease), D02597 (Adalimumab (genetical recombination) (JAN)), D02598 (Infliximab (genetical recombination) (JAN)), D03441 (Certolizumab pegol (genetical recombination) (JAN)), D04358 (Golimumab (genetical recombination) (JAN)), D04687 (Lenalidomide (USAN/INN)), D09813 (Lenalidomide hydrate (JAN))
rect (527,549) (573,566)	/dbget-bin/www_bget?hsa:3458+H00083+H00084	3458 (IFNG), H00083 (Allograft rejection), H00084 (Graft-versus-host disease)
rect (527,571) (573,588)	/dbget-bin/www_bget?hsa:3586+H00083+H00084	3586 (IL10), H00083 (Allograft rejection), H00084 (Graft-versus-host disease)
rect (677,638) (723,655)	/dbget-bin/www_bget?hsa:712+hsa:713+hsa:714+H00102	712 (C1QA), 713 (C1QB), 714 (C1QC), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (730,638) (776,655)	/dbget-bin/www_bget?hsa:720+hsa:721+H00080+H00102	720 (C4A), 721 (C4B), H00080 (Systemic lupus erythematosus), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (256,141) (302,158)	/dbget-bin/www_bget?hsa:712+hsa:713+hsa:714+H00102	712 (C1QA), 713 (C1QB), 714 (C1QC), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (309,141) (355,158)	/dbget-bin/www_bget?hsa:720+hsa:721+H00080+H00102	720 (C4A), 721 (C4B), H00080 (Systemic lupus erythematosus), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (283,118) (329,135)	/dbget-bin/www_bget?hsa:717+H00080+H00102	717 (C2), H00080 (Systemic lupus erythematosus), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (703,661) (749,678)	/dbget-bin/www_bget?hsa:717+H00080+H00102	717 (C2), H00080 (Systemic lupus erythematosus), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (183,471) (229,488)	/dbget-bin/www_bget?hsa:941+hsa:942+D03203+D04295	941 (CD80), 942 (CD86), D03203 (Abatacept (genetical recombination) (JAN)), D04295 (Galiximab (USAN/INN))
rect (265,471) (311,488)	/dbget-bin/www_bget?hsa:940	940 (CD28)
rect (183,448) (229,465)	/dbget-bin/www_bget?hsa:100133583+hsa:3108+hsa:3109+hsa:3111+hsa:3112+hsa:3113+hsa:3115+hsa:3117+hsa:3118+hsa:3119+hsa:3122+hsa:3123+hsa:3125+hsa:3126+hsa:3127+H00079+H00080+H00081+H00082+H00083+H00294+H00295+H00342+H00408	100133583, 3108 (HLA-DMA), 3109 (HLA-DMB), 3111 (HLA-DOA), 3112 (HLA-DOB), 3113 (HLA-DPA1), 3115 (HLA-DPB1), 3117 (HLA-DQA1), 3118 (HLA-DQA2), 3119 (HLA-DQB1), 3122 (HLA-DRA), 3123 (HLA-DRB1), 3125 (HLA-DRB3), 3126 (HLA-DRB4), 3127 (HLA-DRB5), H00079 (Asthma), H00080 (Systemic lupus erythematosus), H00081 (Hashimoto's thyroiditis), H00082 (Graves' disease), H00083 (Allograft rejection), H00294 (Dilated cardiomyopathy (DCM)), H00295 (Viral myocarditis), H00342 (Tuberculosis), H00408 (Type I diabetes mellitus)
rect (571,472) (617,489)	/dbget-bin/www_bget?hsa:100133583+hsa:3108+hsa:3109+hsa:3111+hsa:3112+hsa:3113+hsa:3115+hsa:3117+hsa:3118+hsa:3119+hsa:3122+hsa:3123+hsa:3125+hsa:3126+hsa:3127+H00079+H00080+H00081+H00082+H00083+H00294+H00295+H00342+H00408	100133583, 3108 (HLA-DMA), 3109 (HLA-DMB), 3111 (HLA-DOA), 3112 (HLA-DOB), 3113 (HLA-DPA1), 3115 (HLA-DPB1), 3117 (HLA-DQA1), 3118 (HLA-DQA2), 3119 (HLA-DQB1), 3122 (HLA-DRA), 3123 (HLA-DRB1), 3125 (HLA-DRB3), 3126 (HLA-DRB4), 3127 (HLA-DRB5), H00079 (Asthma), H00080 (Systemic lupus erythematosus), H00081 (Hashimoto's thyroiditis), H00082 (Graves' disease), H00083 (Allograft rejection), H00294 (Dilated cardiomyopathy (DCM)), H00295 (Viral myocarditis), H00342 (Tuberculosis), H00408 (Type I diabetes mellitus)
rect (490,446) (536,463)	/dbget-bin/www_bget?hsa:959+H00093	959 (CD40LG), H00093 (Combined immunodeficiencies (CIDs), including the following nine diseases:)
rect (571,446) (617,463)	/dbget-bin/www_bget?hsa:958+H00093	958 (CD40), H00093 (Combined immunodeficiencies (CIDs), including the following nine diseases:)
rect (496,140) (542,157)	/dbget-bin/www_bget?hsa:221613+hsa:3012+hsa:3013+hsa:3014+hsa:3015+hsa:317772+hsa:474381+hsa:474382+hsa:55506+hsa:55766+hsa:723790+hsa:8329+hsa:8330+hsa:8331+hsa:8332+hsa:8334+hsa:8335+hsa:8336+hsa:8337+hsa:8338+hsa:83740+hsa:85235+hsa:8969+hsa:92815+hsa:94239+hsa:9555	221613 (HIST1H2AA), 3012 (HIST1H2AE), 3013 (HIST1H2AD), 3014 (H2AFX), 3015 (H2AFZ), 317772 (HIST2H2AB), 474381 (H2AFB2), 474382 (H2AFB1), 55506 (H2AFY2), 55766 (H2AFJ), 723790 (HIST2H2AA4), 8329 (HIST1H2AI), 8330 (HIST1H2AK), 8331 (HIST1H2AJ), 8332 (HIST1H2AL), 8334 (HIST1H2AC), 8335 (HIST1H2AB), 8336 (HIST1H2AM), 8337 (HIST2H2AA3), 8338 (HIST2H2AC), 83740 (H2AFB3), 85235 (HIST1H2AH), 8969 (HIST1H2AG), 92815 (HIST3H2A), 94239 (H2AFV), 9555 (H2AFY)
rect (548,140) (594,157)	/dbget-bin/www_bget?hsa:128312+hsa:158983+hsa:255626+hsa:286436+hsa:3017+hsa:3018+hsa:440689+hsa:8339+hsa:8340+hsa:8341+hsa:8342+hsa:8343+hsa:8344+hsa:8345+hsa:8346+hsa:8347+hsa:8348+hsa:8349+hsa:85236+hsa:8970	128312 (HIST3H2BB), 158983 (H2BFWT), 255626 (HIST1H2BA), 286436 (H2BFM), 3017 (HIST1H2BD), 3018 (HIST1H2BB), 440689 (HIST2H2BF), 8339 (HIST1H2BG), 8340 (HIST1H2BL), 8341 (HIST1H2BN), 8342 (HIST1H2BM), 8343 (HIST1H2BF), 8344 (HIST1H2BE), 8345 (HIST1H2BH), 8346 (HIST1H2BI), 8347 (HIST1H2BC), 8348 (HIST1H2BO), 8349 (HIST2H2BE), 85236 (HIST1H2BK), 8970 (HIST1H2BJ)
rect (496,162) (542,179)	/dbget-bin/www_bget?hsa:126961+hsa:3020+hsa:3021+hsa:333932+hsa:440093+hsa:644950+hsa:653604+hsa:8290+hsa:8350+hsa:8351+hsa:8352+hsa:8353+hsa:8354+hsa:8355+hsa:8356+hsa:8357+hsa:8358+hsa:8968	126961 (HIST2H3C), 3020 (H3F3A), 3021 (H3F3B), 333932 (HIST2H3A), 440093 (H3F3C), 644950, 653604 (HIST2H3D), 8290 (HIST3H3), 8350 (HIST1H3A), 8351 (HIST1H3D), 8352 (HIST1H3C), 8353 (HIST1H3E), 8354 (HIST1H3I), 8355 (HIST1H3G), 8356 (HIST1H3J), 8357 (HIST1H3H), 8358 (HIST1H3B), 8968 (HIST1H3F)
rect (548,162) (594,179)	/dbget-bin/www_bget?hsa:121504+hsa:554313+hsa:8294+hsa:8359+hsa:8360+hsa:8361+hsa:8362+hsa:8363+hsa:8364+hsa:8365+hsa:8366+hsa:8367+hsa:8368+hsa:8369+hsa:8370	121504 (HIST4H4), 554313 (HIST2H4B), 8294 (HIST1H4I), 8359 (HIST1H4A), 8360 (HIST1H4D), 8361 (HIST1H4F), 8362 (HIST1H4K), 8363 (HIST1H4J), 8364 (HIST1H4C), 8365 (HIST1H4H), 8366 (HIST1H4B), 8367 (HIST1H4E), 8368 (HIST1H4L), 8369 (HIST1H4G), 8370 (HIST2H4A)
rect (519,202) (565,219)	/dbget-bin/www_bget?hsa:6737+hsa:6738	6737 (TRIM21), 6738 (TROVE2)
rect (613,140) (659,157)	/dbget-bin/www_bget?hsa:6628	6628 (SNRPB)
rect (613,162) (659,179)	/dbget-bin/www_bget?hsa:6632+hsa:6634	6632 (SNRPD1), 6634 (SNRPD3)
rect (678,140) (724,157)	/dbget-bin/www_bget?hsa:2903+D00711+D00848+D01445+D02102+D02410+D02973+D03100+D03679+D03742+D03746+D03878+D04226+D04308+D04728+D04905+D05145+D05447+D05453+D05714+D06204+D07283+D08098+D08121+D08122+D08174+D08195	2903 (GRIN2A), D00711 (Ketamine hydrochloride (JP16/USP)), D00848 (Dextromethorphan hydrobromide hydrate (JP16)), D01445 (Ifenprodil tartrate (JP16)), D02102 (Methadone hydrochloride (USP)), D02410 (Selfotel (USAN/INN)), D02973 (Aptiganel hydrochloride (USAN)), D03100 (Besonprodil (USAN)), D03679 (Delucemine hydrochloride (USAN)), D03742 (Dextromethorphan (USP)), D03746 (Dextrorphan hydrochloride (USAN)), D03878 (Dizocilpine maleate (USAN)), D04226 (Flupirtine maleate (USAN)), D04308 (Gavestinel (USAN/INN)), D04728 (Licostinel (USAN/INN)), D04905 (Memantine hydrochloride (JAN/USAN)), D05145 (Neramexane mesylate (USAN)), D05447 (Perzinfotel (USAN/INN)), D05453 (Phencyclidine hydrochloride (USAN)), D05714 (Remacemide hydrochloride (USAN)), D06204 (Traxoprodil mesylate (USAN)), D07283 (Esketamine (INN)), D08098 (Ketamine (INN)), D08121 (Levomethadone (INN)), D08122 (Levomethadone hydrochloride), D08174 (Memantine (INN)), D08195 (Methadone (BAN))
rect (625,202) (671,219)	/dbget-bin/www_bget?hsa:81+hsa:87+hsa:88+hsa:89	81 (ACTN4), 87 (ACTN1), 88 (ACTN2), 89 (ACTN3)
rect (678,202) (724,219)	/dbget-bin/www_bget?hsa:712+hsa:713+hsa:714+H00102	712 (C1QA), 713 (C1QB), 714 (C1QC), H00102 (Classic complement pathway component defects, including the following eight diseases:)
rect (572,202) (618,219)	/dbget-bin/www_bget?hsa:6741	6741 (SSB)
rect (678,162) (724,179)	/dbget-bin/www_bget?hsa:2904+D00711+D00848+D01445+D02102+D02410+D02973+D03100+D03679+D03742+D03746+D03878+D04226+D04308+D04728+D04905+D05145+D05447+D05453+D05714+D06204+D07283+D08098+D08121+D08122+D08174+D08195	2904 (GRIN2B), D00711 (Ketamine hydrochloride (JP16/USP)), D00848 (Dextromethorphan hydrobromide hydrate (JP16)), D01445 (Ifenprodil tartrate (JP16)), D02102 (Methadone hydrochloride (USP)), D02410 (Selfotel (USAN/INN)), D02973 (Aptiganel hydrochloride (USAN)), D03100 (Besonprodil (USAN)), D03679 (Delucemine hydrochloride (USAN)), D03742 (Dextromethorphan (USP)), D03746 (Dextrorphan hydrochloride (USAN)), D03878 (Dizocilpine maleate (USAN)), D04226 (Flupirtine maleate (USAN)), D04308 (Gavestinel (USAN/INN)), D04728 (Licostinel (USAN/INN)), D04905 (Memantine hydrochloride (JAN/USAN)), D05145 (Neramexane mesylate (USAN)), D05447 (Perzinfotel (USAN/INN)), D05453 (Phencyclidine hydrochloride (USAN)), D05714 (Remacemide hydrochloride (USAN)), D06204 (Traxoprodil mesylate (USAN)), D07283 (Esketamine (INN)), D08098 (Ketamine (INN)), D08121 (Levomethadone (INN)), D08122 (Levomethadone hydrochloride), D08174 (Memantine (INN)), D08195 (Methadone (BAN))
rect (286,372) (399,406)	/kegg-bin/show_pathway?hsadd04660	hsadd04660: T cell receptor signaling pathway
rect (482,371) (595,405)	/kegg-bin/show_pathway?hsadd04514	hsadd04514: Cell adhesion molecules (CAMs)
rect (185,545) (298,579)	/kegg-bin/show_pathway?hsadd04612	hsadd04612: Antigen processing and presentation
rect (337,619) (450,653)	/kegg-bin/show_pathway?hsadd04060	hsadd04060: Cytokine-cytokine receptor interaction
rect (337,686) (450,720)	/kegg-bin/show_pathway?hsadd04630	hsadd04630: Jak-STAT signaling pathway
rect (1011,196) (1124,230)	/kegg-bin/show_pathway?hsadd04610	hsadd04610: Complement and coagulation cascades
rect (841,632) (954,677)	/kegg-bin/show_pathway?hsadd04670	hsadd04670: Leukocyte transendothelial migration
rect (646,331) (759,365)	/kegg-bin/show_pathway?hsadd04662	hsadd04662: B cell receptor signaling pathway
rect (40,45) (312,70)	/dbget-bin/www_bget?hsa05322	hsadd05322: Systemic lupus erythematosus