UniProtKB-GOA README FOR GP_INFORMATION.GOA_UNIPROT
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1.  Contents
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1.  Contents
2.  Introduction

2.  Introduction
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UniProtKB-GOA (GO Annotation@EBI) is a project run by the European
Bioinformatics Institute that aims to provide assignments
of gene products to the Gene Ontology (GO) resource.  The
goal of the Gene Ontology Consortium is to produce a dynamic
controlled vocabulary that can be applied to all eukaryotes,
even while the knowledge of the gene product roles in cells is
still accumulating and changing.

In the UniProtKB-GOA project, this vocabulary is applied to all proteins
described in the UniProt (Swiss-Prot and TrEMBL) Knowledgebase.

For full information on the UniProtKB-GOA project, please go to:
http://www.ebi.ac.uk/GOA

This readme describes the format of the gp_information.goa_uniprot file. 
This file has been created to supply additional information on the 
DB_OBJECT_ID that has been provided with annotations.
This file currently consists of 11 tab-separated fields, and the contents of 
these fields are described below. However as the format of this file is 
currently being discussed by the GO Consortium, it is therefore subject to change.
For further information please see:
http://wiki.geneontology.org/index.php/Annotation_File_Format_Proposal#Proposed_file_format

This file currently consists of 11 tab-separated fields. Their contents are described below.

1.  DB
Database from which annotated entry has been taken.
This file will contain one of either: UniProtKB or IPI
This field equates to column 1 in the GAF2.0 format.

2. DB_Subset
The database subset from which the entity being described has been taken.
This information will only be supplied for UniProtKB, where this field
will be one of Swiss-Prot or TrEMBL.
This field is only supplied by the gp_information.goa_uniprot file.

3. DB_Object_ID
A unique identifier in the database for the entity being described.
Here: an accession number or identifier of the annotated protein
- a UniProtKB accession number, UniProtKB isoform identifier or IPI identifier
Examples: 
O00165
O00165-1
This field equates to column 2 (or column 17 in the case of isoform identifiers) in the GAF2.0 format.

4. DB_Object_Symbol
A (unique and valid) symbol (gene name) that corresponds to the DB_Object_ID.
An officially approved gene symbol will be used in this field when available.
Alternatively, other gene symbols or locus names are applied.
If no symbols are available, the identifier applied in column 2 will be used.
Examples:
G6PC
CYB561
MGCQ309F3
C10H14ORF1
This field equates to column 3 in the GAF2.0 format.

5. DB_Object_Name
The name of the entity being described. The full UniProt protein name will be present here,
if available from UniProtKB. If a name cannot be added, this field will be left empty.
Examples: 
Glucose-6-phosphatase
Cellular tumor antigen p53
Coatomer subunit beta
This field equates column 10 in the GAF2.0 format.

6. DB_Object_Synonym
Gene_symbol [or other text]
Alternative gene symbol(s), IPI identifier(s) and UniProtKB/Swiss-Prot identifiers are
provided, pipe-separated, if available from UniProtKB. If none of these identifiers
have been supplied, the field will be left empty.
Examples:
RNF20|BRE1A|IPI00690596|BRE1A_BOVIN
IPI00706050
MMP-16|IPI00689864
This field equates to column 11 in the GAF2.0 format.

7. DB_Object_Type
The kind of entity that DB_Object_ID identifies.
Examples: protein, isoform, protein_structure
This field equates to column 12 in the GAF2.0 format

8. Taxon
Identifier for the species to which the described entity relates.
Example: taxon:9606
This field equates to column 13 in the GAF2.0 format.

9. Annotation_Target_Set
A description of the list in which the protein has been included for prioritized annotation.
Examples: 
BHF-UCL
KRUK
Reference_Genome
This field is only supplied by the gp_information.goa_uniprot file.

10. Annotation_Completed
The date when a curator has indicated that the protein's GO annotation record had been 
comprehensively curated.
Example: 20080101
This field is only supplied by the gp_information.goa_uniprot file.

11. Parent_Object_ID
This field supplies the relationship between the DB_Object_ID and a top-level 
UniProtKB accession number, where the DB_Object_ID is an isoform identifier.
Example: UniProtKB:P21678
This field is only supplied by the gp_information.goa_uniprot file.