#### README #### IMPORTANT: Please note you can download correlation data tables, supported by Ensembl, via the highly customisable BioMart and EnsMart data mining tools. See http://metazoa.ensembl.org/biomart/martview or http://www.ebi.ac.uk/biomart/ for more information. #################### Fasta Peptide dumps #################### These files hold the protein translations of Ensembl gene predictions. ----------- FILE NAMES ------------ The files are consistently named following this pattern: .....fa.gz : The systematic name of the species. : The assembly build name. : The version of Ensembl Genomes from which the data was exported. : pep for peptide sequences * 'pep.all' - the super-set of all translations resulting from Ensembl known or novel gene predictions. * 'pep.abinitio' translations resulting from 'ab initio' gene prediction algorithms such as SNAP and GENSCAN. In general, all 'ab initio' predictions are based solely on the genomic sequence and not any other experimental evidence. Therefore, not all GENSCAN or SNAP predictions represent biologically real proteins. fa : All files in these directories represent FASTA database files gz : All files are compacted with GNU Zip for storage efficiency. EXAMPLES (Note: Most species do not sequences for each different ) for Human: Homo_sapiens.NCBI36.pep.all.fa.gz contains all known and novel peptides Homo_sapiens.NCBI36.pep.abinitio.fa.gz contains all abinitio predicted peptide Difference between known and novel ---------------------------------- Protein models that can be mapped to species-specific entries in Swiss-Prot, RefSeq or SPTrEMBL are referred to in Ensembl as known genes. Those that cannot be mapped are called novel (e.g. genes predicted on the basis of evidence from closely related species). ------------------------------- FASTA Sequence Header Lines ------------------------------ The FASTA sequence header lines are designed to be consistent across all types of Ensembl FASTA sequences. This gives enough information for the sequence to be identified outside the context of the FASTA database file. General format: >ID SEQTYPE:STATUS LOCATION GENE TRANSCRIPT Example of Ensembl Peptide header: >ENSP00000328693 pep:novel chromosome:NCBI35:1:904515:910768:1 gene:ENSG00000158815:transcript:ENST00000328693 ^ ^ ^ ^ ^ ^ ID | | LOCATION GENE:stable gene ID | | STATUS TRANSCRIPT: stable transcript ID SEQTYPE