Today I finished validating a CpG O/E workflow Steven put together by analyzing the C. gigas transcriptome and comparing it to the results of Gavery and Roberts (2010). The results agreed well. Notably, there was a similar bimodal distribution of CpG O/E, and major gene categories showed similar levels of CpG O/E (e.g., cell adhesion around 0.7 and DNA metabolism around 0.5).